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Nebulized Albuterol for Congestive Heart Failure Exacerbation

Information source: University of California, San Francisco
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Congestive Heart Failure

Intervention: Albuterol (Drug); Normal Saline (Drug)

Phase: Phase 2/Phase 3

Status: Withdrawn

Sponsored by: University of California, San Francisco

Official(s) and/or principal investigator(s):
John C. Stein, MD., Principal Investigator, Affiliation: University of California, San Francisco

Summary

This is a randomized trial of the use of Albuterol in the setting of acute decompensated Congestive Heart Failure with radiographic evidence of Cardiogenic Pulmonary Edema.

Clinical Details

Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment

Primary outcome: Borg Dyspnea Score

Secondary outcome: Admission

Detailed description: The objective is to carry out a randomized blinded placebo-controlled trial of inhaled Albuterol as an early therapy for patients with decompensated Congestive Heart Failure. Compared to placebo, inhaled Albuterol will improve oxygenation and decrease the need for non-invasive ventilation in patients with Cardiogenic Pulmonary Edema.

Eligibility

Minimum age: 18 Years. Maximum age: 65 Years. Gender(s): Both.

Criteria:

Inclusion Criteria:

- age 18-65 with shortness of breath and history of CHF

- pulmonary edema on chest xr

Exclusion Criteria:

- pregnancy

- clinical or ekg changes to suggest acute coronary syndrome

- history of copd or asthma

- history of albuterol on medication list

Locations and Contacts

University of California, San Francisco, California 94143, United States
Additional Information

Starting date: April 2009
Last updated: October 9, 2013

Page last updated: August 23, 2015

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