Insulin Secretory Capacity in Insulin-Independent Pancreas-Kidney Recipients Compared to Controls
Information source: University Hospital, Gasthuisberg
Information obtained from ClinicalTrials.gov on November 03, 2008
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Kidney Transplantation; Pancreas Transplantation
Intervention: hyperglycemic clamp test (Other)
Phase: N/A
Status: Recruiting
Sponsored by: University Hospital, Gasthuisberg Official(s) and/or principal investigator(s):
Chantal Mathieu, M.D., PhD, Principal Investigator, Affiliation: UZ-Gasthuisberg, Department of Endocrinology
Overall contact:
Chantal Mathieu, M.D., PhD., Phone: 0032/16/346994, Email: chantal.mathieu@uz.kuleuven.ac.be
Summary
To compare functional beta-cell mass using the hyperglycaemic clamp test in
insulin-independent pancreas-kidney recipients with that in non-diabetic kidney recipients
and normal controls as well as with the partially previously reported data in beta-cell
recipients.
Clinical Details
Official title: Insulin Secretory Capacity in Insulin-Independent Pancreas-Kidney Recipients Compared to Non-Diabetic Kidney Recipients, Insulin Independent Recipients of Beta-Cell Grafts and Healthy Controls.
Study design: Diagnostic, Open Label, Parallel Assignment
Primary outcome: insulin secretion during clamp test
Eligibility
Minimum age: 21 Years.
Maximum age: 65 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- kidney pancreas recipients
- kidney recipients
- healthy volunteers
- beta-cell recipients
- immunosuppression with MMF-Tacrolimus
- 1-4 years after transplantation
Exclusion Criteria:
- high doses of steroids
- insulin dependent
Locations and Contacts
Chantal Mathieu, M.D., PhD., Phone: 0032/16/346994, Email: chantal.mathieu@uz.kuleuven.ac.be
Department of Endocrinology, Leuven, UZ-Gasthuisberg, Leuven 3000, Belgium; Recruiting
Pieter Gillard, M.D., Phone: 003216346994, Email: pieter.gillard@uz.kuleuven.ac.be
Pieter Gillard, M.D., Sub-Investigator
Additional Information
Starting date: October 2004
Ending date: January 2010
Last updated: February 6, 2008
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