Anesthesia in Flexible Bronchoscopy for Lung Cancer Diagnostic
Information source: Hospital Pompeia
Information obtained from ClinicalTrials.gov on June 20, 2008
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Lung Cancer
Intervention: propofol (Drug); midazolam (Drug); alfentanil (Drug); lidocaine (Drug)
Phase: Phase 4
Status: Completed
Sponsored by: Hospital Pompeia Official(s) and/or principal investigator(s):
Andre GS Leite, PhD, Principal Investigator, Affiliation: Brazilian Society of Thoracic Surgery
Summary
The objective of the study was to establish which anesthetic procedure used during flexible
bronchoscopy has the lowest index of complications.
Clinical Details
Study design: Treatment, Randomized, Single Blind, Active Control, Factorial Assignment
Detailed description:
This prospective randomized study analyzed 80 patients that underwent flexible bronchoscopy.
Patients were randomly assigned to four groups of 20 patients each according to the
anesthetic combination used: 200 mg topical lidocaine (LID group); 200 mg topical lidocaine
and 2 mg/kg propofol (PPF group); 200 mg topical lidocaine and 20 mcg/kg alfentanil (ALF
group); or 200 mg topical lidocaine and 0. 05 mg/kg midazolam (MID group). Scores were
assigned to patients according to the different variables observed during the endoscopic
procedure; the lower the score, the lower the complication index.
Eligibility
Minimum age: 18 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- The patients included in this study were referred to FBC for the investigation of
bronchial carcinoma (diagnostic procedure).
- Patients included in the study were classified as ASA I, II and II according to the
anesthetic risk classification of the American Society of Anesthesiologists (ASA).
Exclusion Criteria:
- ASA IV classification of anesthesiology risk
- procedure that lasted longer than 15 minutes
- indication of therapeutic bronchoscopy
- cardiac arrhythmia and / or hypoxemia detected at admission.
Locations and Contacts
Hospital Pompeia, Caxias do Sul, RS 95010-005, Brazil
Hospital Medianeira, Caxias do Sul, RS 95040-000, Brazil
General Hospital of Universidade de Caxias do Sul, Caxias do Sul, RS 95070-560, Brazil
Additional Information
Related publications: Pue CA, Pacht ER. Complications of fiberoptic bronchoscopy at a university hospital. Chest. 1995 Feb;107(2):430-2.
Last updated: February 26, 2007
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