Study Comparing CT Scan and Stress Test in Diagnosing Coronary Artery Disease in Patients Hospitalized for Chest Pain
Information source: Montefiore Medical Center
Information obtained from ClinicalTrials.gov on November 03, 2008
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Coronary Artery Disease; Angina Pectoris; Unstable Angina; Acute Coronary Syndrome
Intervention: Coronary Computed Tomography Angiography (Procedure); Stress Nuclear Myocardial Perfusion Imaging (Procedure)
Phase: N/A
Status: Recruiting
Sponsored by: Montefiore Medical Center Official(s) and/or principal investigator(s):
Linda B Haramati, MD, MS, Study Director, Affiliation: Montefiore Medical Center / Albert Einstein College of Medicine
Jeffrey M Levsky, MD, PhD, Principal Investigator, Affiliation: Montefiore Medical Center / Albert Einstein College of Medicine
Overall contact:
Linda B Haramati, MD, MS, Phone: 718-920-7458, Email: lharamati@aecom.yu.edu
Summary
The purpose of this study is to determine whether coronary artery CT scanning or nuclear
stress testing is better at diagnosing chest pain patients with coronary artery disease to
select appropriate candidates for coronary catheterization and re-vascularization.
Clinical Details
Official title: A Randomized Trial Comparing Multi-Detector Coronary CT Angiography and Stress Myocardial Perfusion Imaging as the Initial Test for the Diagnosis of Coronary Artery Disease in Intermediate Risk Patients Admitted for Chest Pain
Study design: Diagnostic, Randomized, Single Blind (Outcomes Assessor), Parallel Assignment, Safety/Efficacy Study
Primary outcome: Coronary catheterization that does not lead to re-vascularization
Secondary outcome: Length of Hospital Stay (time to discharge)Non-fatal myocardial infarction Death (all cause) Post-test renal dysfunction
Eligibility
Minimum age: 21 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- patient admitted for chest pain or pressure
- patient at intermediate short term risk of MI or death (AHA/ACC guidelines)
Exclusion Criteria:
- prior diagnosis of coronary artery disease
- evidence of ongoing myocardial infarction (and other high risk criteria per AHA/ACC
guidelines)
- contraindications to EKG-gated CT scanning with iodinated intravenous contrast under
beta-blockade
- pregnancy
- presence of an implanted pacemaker or defibrillator
- stress myocardial perfusion imaging, coronary CTA or coronary catheterization within
the last 6 months
Locations and Contacts
Linda B Haramati, MD, MS, Phone: 718-920-7458, Email: lharamati@aecom.yu.edu
Moses Division, Montefiore Medical Center, Bronx, New York 10467, United States; Recruiting
Additional Information
Starting date: July 2008
Ending date: June 2011
Last updated: September 19, 2008
|
