The Effects of Xalatan, Travatan and Lumigan on Skin Pigmentation Near the Eye
Information source: Summa Health System
Information obtained from ClinicalTrials.gov on October 04, 2010
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Glaucoma; Periocular Skin Pigmentation Changes
Intervention: Latanoprost (Drug); Bimatoprost (Drug); Travoprost (Drug)
Phase: Phase 4
Sponsored by: Summa Health System
Official(s) and/or principal investigator(s):
Deepak P Edward, MD, Principal Investigator, Affiliation: Summa Health System
Smajo Osmanovic, MD, Principal Investigator, Affiliation: Arlington eye Associates
Deepak P Edward, MD, Phone: 330-375-3867, Email: Edwardd@summa-health.org
The purpose of this study is to study changes in skin color that may be caused by using one
of the three eye medicines: Xalatan, Travatan or lumigan.
Official title: The Effects of Latanoprost, Bimatoprost and Travoprost on Periocular Skin Pigmentation
Study design: Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
Primary outcome: skin pigmentation changes
One uncommon side effect of prostaglandin eye drops is a change in color of the skin around
the eyes, which is reversible. There are three different brands of the medicine which are
equally effective in lowering eye pressure but their likelihood of changing skin color is
unknown. Qualifying patients will be randomly assigned to use one of the three eye drops. We
will take skin color measurements from several locations on the face over one year to
measure pigmentation changes.
Minimum age: 30 Years.
Maximum age: N/A.
- patients recently diagnosed with primary open angle glaucoma or ocular hypertension
- Caucasian and African American ethnicities
- Male and Female
- Age 30 and above
- A history of ocular medication use within the last 12 months
- Inflammatory/ allergic skin diseases or dermatitis
- presence of periocular hyperpigmented skin lesions
- Systemic pigmentation disorders
- Use of systemic drugs that can affect skin pigmentation
- Visitation of tanning salons, or use of self tanning products
- Pregnancy or patients planning to become pregnant in the near future
Locations and Contacts
Deepak P Edward, MD, Phone: 330-375-3867, Email: Edwardd@summa-health.org
Arlington Eye Physicians, Arlington Heights, Illinois 60005, United States; Recruiting
Smajo Osmanovic, MD, Phone: 847-394-1414
Smajo Osmanovic, MD, Sub-Investigator
Summa Health System, Akron, Ohio 44304, United States; Recruiting
Deepak P Edward, MD, Phone: 330-375-3867
Marianne A Wiest, BS, Phone: 330-375-6655, Email: firstname.lastname@example.org
Deepak P Edward, MD, Principal Investigator
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Starting date: March 2008
Last updated: July 19, 2010