Moxifloxacin Versus Ofloxacin Plus Metronidazole in Uncomplicated Pelvic Inflammatory Disease: Multicenter Randomized Controlled Trials
Information source: Istanbul Bakirkoy Maternity and Children Diseases Hospital
ClinicalTrials.gov processed this data on August 23, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Pelvic Inflammatory Disease
Intervention: Moxifloxacin (Drug); Ofloxacin (Drug); Metronidazole (Drug)
Phase: Phase 4
Status: Completed
Sponsored by: Istanbul Bakirkoy Maternity and Children Diseases Hospital Official(s) and/or principal investigator(s): Kemal Gungorduk, md, Study Chair, Affiliation: T.C.S.B. Kanıni Sultan Suleyman Training Hospital
Summary
We aimed to compare efficacy and safety of combination therapy with oral ofloxacin, 400 mg
twice daily, plus oral metronidazole, 500 mg twice daily, for 14 days, with moxifloxacin
monotherapy, 400 mg once daily, for 14 days
Clinical Details
Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment
Primary outcome: Clinically cure
Secondary outcome: Microbiological cure
Eligibility
Minimum age: 14 Years.
Maximum age: 45 Years.
Gender(s): Female.
Criteria:
Inclusion Criteria:
1. Women diagnosed uncomplicated PID
2. Patients age are between 14 with 45
3. Pelvic tenderness and vaginal discharge
Exclusion Criteria:
1. Urinary Tract Enfections
2. Tubo-ovarian abscess and complicated PID
3. Hıstory of antibiotics treatment
4. Other pelvic pain causes
5. Endometriosis
6. Delivery,abortion and surgery within last months
Locations and Contacts
T.C.S.B Mardin Women and Children Hospital, Mardin 47000, Turkey
T.C.S.B. Şişli Etfal Training Research Hospital, Şişli 34150, Turkey
T.C.S.B. İstanbul Training Research Hospital, Samatya, Fatih 34180, Turkey
T.C.S.B. Kanuni Sultan Suleyman Training Hospital, İstanbul, Kucukcekmece 34280, Turkey
Additional Information
Starting date: June 2010
Last updated: August 27, 2013
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