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Continuous Glucose Monitoring in Critically Ill Patients

Information source: Medical University of Vienna
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Critical Illness

Intervention: continuous subcutaneous glucose monitoring (Device); continuous subcutaneous glucose monitoring (Device)

Phase: N/A

Status: Completed

Sponsored by: Medical University of Vienna

Official(s) and/or principal investigator(s):
Ulrike Holzinger, MD, Principal Investigator, Affiliation: Medical University of Vienna, Department of Medicine III

Summary

The purpose of this study is to determine whether subcutaneous continuous glucose monitoring in critically ill patients is clinically feasible accurate and reliable.

Clinical Details

Official title: Accuracy and Reliability of Continuous Glucose Monitoring in Critically Ill Patients With Shock Requiring Norepinephrine Therapy

Study design: Allocation: Non-Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Supportive Care

Primary outcome: correlation of continuous glucose monitoring derived glucose values and arterial blood glucose measurements in critically ill patients with and without shock

Secondary outcome: influence of norepinephrine therapy, body mass index, severity of Illness (APACHE III, SAPS II) and blood glucose level on correlation

Detailed description: Hyperglycemia is is associated with more complications and higher morbidity and mortality in critically ill patients. Therefore, strict glycemic control with a target blood glucose level between 80 and 110 mg/dl is recommended. Intensive insulin therapy requires continuous intravenous insulin infusion according to an algorithm and frequent blood glucose measurements. Implementation of intensive insulin therapy increases workload for both physicians and especially for nurses. Continuous glucose measurement would facilitate blood glucose control in critically ill patients. Numerous studies have shown accuracy of the subcutaneous continuous glucose monitoring derived glucose values compared to blood glucose measurements in diabetics. Studies evaluating the subcutaneous continuous glucose monitoring in an inpatient-population especially in an ICU-setting are rare. Therefore the aim of this study is the prospective evaluation of continuous subcutaneous glucose monitoring in critically ill patients with circulatory shock demanding norepinephrine therapy as compared to critically ill patients without shock.

Eligibility

Minimum age: 19 Years. Maximum age: N/A. Gender(s): Both.

Criteria:

Inclusion Criteria:

- Admitted patients expected to stay >48h either with circulatory shock requiring

norepinephrine therapy or without circulatory shock. Exclusion Criteria:

- Admitted patients expected to stay <48h

Locations and Contacts

Medical University of Vienna, Vienna 1090, Austria
Additional Information

Starting date: April 2005
Last updated: February 19, 2008

Page last updated: August 23, 2015

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