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Analgesic Effect Between TAP Block and Continuous Wound Infusion in Abdominoplasty Surgery

Information source: University Hospital of Liege
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Surgery of Abdominoplasty With Flank Liposuction

Intervention: Transverse abdominal plan block (Procedure); Continuous wound infusion (Procedure)

Phase: N/A

Status: Recruiting

Sponsored by: University Hospital of Liege

Official(s) and/or principal investigator(s):
Jean-Pierre H Lecoq, Md, PhD, Principal Investigator, Affiliation: University of Liege, University Hospital

Overall contact:
Jean-Pierre H Lecoq, MD, PhD, Phone: 003243667180, Email: jplecoq@chu.ulg.ac.be

Summary

The purpose of this randomized controlled study is to compare the postoperative analgesic effect of a continuous wound infusion of local anesthetics and a sole transverse abdominal plan (TAP) regional block in the surgery of Abdominoplasty Combined With Flank Liposuction. Local anesthetics products used are ropivacaine combined with clonidine. Similar amount of local anesthetics and clonidine are used.

Clinical Details

Official title: Comparative Analgesic Effect Between Continuous Wound Infusion and Transverse Abdominal Plan Block for Abdominoplasty Surgery

Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Primary outcome: Pain score expressed on a visual analogue scale

Secondary outcome:

Piritramide consumption on Patient Controlled Analgesia (PCA) device

Scale of nausea

Scale of sedation

Scale of patient's satisfaction

Number of patients with adverse events

Detailed description: In a first group, patients receive, after induction of anaesthesia and before surgery, a TAP block (transverse abdominal plan block) with 3mg/kg Ropivacaine 0. 5% (maximum 200 mg) and 150 microg Clonidine. In a second group, before skin closure, a multiholes catheter was inserted beyond the skin. 20 mg Ropivacaine 0. 2% added with 150 microg Clonidine was injected as bolus dose through this catheter followed by a continuous infusion of Ropivacaine 0. 2% 10ml per hour during the following 9 hours (total dose of 200 mgr).

Eligibility

Minimum age: 18 Years. Maximum age: 70 Years. Gender(s): Female.

Criteria:

Inclusion Criteria:

- Patients scheduled for abdominoplasty combined with flank liposuction

Exclusion Criteria:

- Allergy to local anesthetics or clonidine

- Coagulation disorders

- History of chronic pain

- Alcohol or drugs dependance

- Refusal of the patients

Locations and Contacts

Jean-Pierre H Lecoq, MD, PhD, Phone: 003243667180, Email: jplecoq@chu.ulg.ac.be

University of Liege, University Hospital, Liege 4000, Belgium; Recruiting
Jean-Pierre H Lecoq, MD, PhD, Phone: 003243667180, Email: jplecoq@chu.ulg.ac.be
Jean-Fran├žois Brichant, Md, PhD, Phone: 003243667180, Email: anesrea@ulg.ac.be
Jean-Pierre H Lecoq, MD, PhD, Principal Investigator
Additional Information

Starting date: June 2013
Last updated: May 12, 2015

Page last updated: August 23, 2015

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