Comparison of Sevoflurane and Isoflurane Anesthesia for Benign Breast Tumor Excision
Information source: Nanjing Medical University
Information obtained from ClinicalTrials.gov on June 20, 2008
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Breast Neoplasms
Intervention: Sevoflurane (Drug); Isoflurane (Drug)
Phase: Phase 4
Status: Completed
Sponsored by: Nanjing Medical University Official(s) and/or principal investigator(s):
XiaoFeng Shen, MD, Study Director, Affiliation: Nanjing Medical University
Summary
Generally, benign breast tumors are excised under the local anesthesia. But such action was
so invasive that every patient would experience the physiological and psychological stimuli
unavoidably. Sevoflurane was advised as a better inhalational anesthesic for its "easy
come,easy go" property during short-lasting operations than isoflurane. We purposed that
sevoflurane would be a superior anesthesic for benign breast tumor excision than isoflurane
with relative less alteration in hemodynamics, less postoperative side effects and
easily-control the depth of anesthesia.
Clinical Details
Official title: Anesthesia With Sevoflurane and Isoflurane for Excision Surgeries in Benign Breast Tumors
Study design: Treatment, Randomized, Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Active Control, Parallel Assignment, Safety/Efficacy Study
Primary outcome: Time of induction, maintenance and resuscitation
Secondary outcome: Intraoperative hemodynamics;
Postoperative side effects;
Eligibility
Minimum age: 18 Years.
Maximum age: 64 Years.
Gender(s): Female.
Criteria:
Inclusion Criteria:
- Chinese
- Diagnosed benign breast tumor patients
- 18-64 yrs
Exclusion Criteria:
- Allergic to any interventional drugs
- Organic dysfunction
- Long-lasting PACU staying
Locations and Contacts
Nanjing Maternal and Child Care Hospital, Nanjing, Jiangsu 210004, China
Additional Information
Starting date: March 2007
Ending date: December 2007
Last updated: April 18, 2008
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