Isoflurane at Subanesthetic Concentrations - 6
Information source: University of Chicago
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Opioid-Related Disorders; Substance-Related Disorders
Intervention: 40% Nitrous oxide (Drug); Sham comparator (Other); 0.2% isoflurane (Drug); 0.4% isoflurane (Drug); 0.6% isoflurane (Drug)
Phase: Phase 2
Status: Completed
Sponsored by: University of Chicago Official(s) and/or principal investigator(s):
James Zacny, Ph.D., Principal Investigator, Affiliation: University of Chicago
Summary
The purpose of this study is to conduct experiments to examine subjective and reinforcing
effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug
abusers and preference procedures will be used to assess reinforcing effects. To test the
hypothesis that isoflurane at subanesthetic concentrations does not reduce cold-water
immersion pain in healthy volunteers.
Clinical Details
Official title: Isoflurane at Subanesthetic Concentrations
Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
Primary outcome: Pain response
Eligibility
Minimum age: 21 Years.
Maximum age: 34 Years.
Gender(s): Male.
Criteria:
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Locations and Contacts
University of Chicago, Anesthesia & Critical Care, Chicago, Illinois 60637, United States
Additional Information
Related publications: Anesthesiology, 1995, 83: A287
Starting date: January 1995
Last updated: May 26, 2015
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