The Effect of Antihypertensive Agents Concerning With Hemodynamics and Reduction of Anaesthetics in Orthognathic Surgery
Information source: Yonsei University
ClinicalTrials.gov processed this data on August 23, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Orthognathic Surgery
Intervention: b-blocker(Atenolol) (Drug); ACE inhibitor(Enapril) (Drug); control (Other)
Phase: N/A
Status: Completed
Sponsored by: Yonsei University
Summary
For those who receive hypotensive anesthesia in orthognathic surgeries, the investigators
premedicate with anti-hypertensive agent so that it decreases the occurence of tachycardia
and the rebound hypertension due to hypotensive anesthesia, enabling us to compare
hemodynamic stability and reduction of anesthetic agents during the operation.
Clinical Details
Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Supportive Care
Primary outcome: the influence of antihypertensive agents on hemodynamic stability
Secondary outcome: reduction of anaesthetics with control
Eligibility
Minimum age: 18 Years.
Maximum age: 29 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
1. ASA class I-II
2. obtaining written informed consent from the parents
3. aged 18-29 years who were undergoing orthognathic surgery.
Exclusion Criteria:
1. Hypertension patients with anti-hypertensive agents
2. chronic renal failure or End stage renal disease patients.
3. renal artery stenosis history.
4. Patients who are with medication due to systemic disease.
5. symptomatic asthma
6. Drug hyperactivity
7. neurological or psychiatric illnesses
8. mental retardation
9. patients who can`t read the consent form due to illiterate or foreigner
Locations and Contacts
Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul 120-752, Korea, Republic of
Additional Information
Starting date: August 2012
Last updated: March 31, 2014
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