Study Evaluating the Effects of DVS SR and Duloxetine on the Pharmacokinetics of Desipramine in Healthy Subjects
Information source: Wyeth
Information obtained from ClinicalTrials.gov on June 20, 2008
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Depression; Depressive Disorder; Depressive Disorder, Major
Intervention: desvenlafaxine SR (Drug); desipramine (Drug); duloxetine (Drug)
Phase: Phase 3
Status: Completed
Sponsored by: Wyeth Official(s) and/or principal investigator(s):
Medical Monitor, Study Director, Affiliation: Wyeth
Summary
The purpose of this study is to evaluate the effects of multiple doses of DVS SR and
duloxetine on the pharmacokinetics of a single dose of desipramine in healthy subjects.
Clinical Details
Official title: A Randomized, Open-Label, Crossover, Drug Interaction Study to Evaluate the Effects of DVS SR And Duloxetine on the Pharmacokinetics of Desipramine in Healthy Subjects
Study design: Treatment, Randomized, Open Label, Active Control, Crossover Assignment, Pharmacokinetics Study
Primary outcome: The primary outcome of the study is to evaluate the effects of multiple doses of DVS SR and duloxetine on the pharmacokinetics of a single dose of desipramine in healthy subjects.
Eligibility
Minimum age: 18 Years.
Maximum age: 55 Years.
Gender(s): Both.
Criteria:
1. Healthy men and women between 18 to 55 years of age.
2. Healthy as determined by the investigator on the basis of medical history and physical
examination, laboratory test results, vital signs and a 12-lead electrocardiogram.
3. History of being a nonsmoker for a least 1 year.
Locations and Contacts
Neptune, New Jersey 07753, United States
Additional Information
Starting date: September 2006
Ending date: September 2006
Last updated: May 25, 2007
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