Prospective Comparison of Ampicillin / Amoxicillin Versus Ceftriaxone for the Treatment of Salmonella Infections in AIDS Patients
Information source: NIH AIDS Clinical Trials Information Service
Information obtained from ClinicalTrials.gov on June 20, 2008
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: HIV Infections; Salmonella Infections
Intervention: Ceftriaxone sodium (Drug); Ampicillin sodium (Drug); Amoxicillin trihydrate (Drug)
Phase: N/A
Status: Completed
Sponsored by: University of Southern California
Summary
To compare the effectiveness of standard treatment with parenteral ampicillin and oral
amoxicillin compared to initial daily therapy with ceftriaxone followed by 3 times weekly
suppressive treatment for salmonella infections in AIDS patients.
Clinical Details
Official title: Prospective Comparison of Ampicillin / Amoxicillin Versus Ceftriaxone for the Treatment of Salmonella Infections in AIDS Patients
Study design: Treatment, Dose Comparison
Eligibility
Minimum age: 18 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Exclusion Criteria
Co-existing Condition:
Patients with the following are excluded:
- Type I hypersensitivity to beta-lactam antibiotics.
- Not expected to survive 12 weeks.
- In a coma or with other central nervous system (CNS) impairment.
Patients with the following are excluded:
- Type I hypersensitivity to beta-lactam antibiotics.
- Not expected to survive 12 weeks.
- In a coma or with other central nervous system (CNS) impairment.
Prior Medication:
Excluded within 48 hours of study entry:
- Treatment with an antibiotic active in vitro against Salmonella.
HIV infection, AIDS, or AIDS related complex (ARC).
- Salmonella bacteremia or positive stool culture in patient with 3 or more stools per
day.
Locations and Contacts
Los Angeles County - USC Med Ctr, Los Angeles, California 90033, United States
Additional Information
Last updated: June 23, 2005
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