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Effect of Brimonidine Tartrate Ophthalmic Solution 0.15% on Pupil Diameter in Normal Eyes

Information source: Walter Reed Army Medical Center
Information obtained from ClinicalTrials.gov on June 20, 2008
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Healthy

Intervention: Brimonidine tartrate ophthalmic solution 0.15% (Alphagan P) (Drug)

Phase: N/A

Status: Completed

Sponsored by: Walter Reed Army Medical Center

Official(s) and/or principal investigator(s):
KRAIG S. BOWER, MD, Principal Investigator, Affiliation: Walter Reed Army Medical Center

Summary

The objective of this study is to evaluate the effect of brimonidine tartrate ophthalmic solution 0. 15% (Alphagan P) on pupil diameter under different luminance conditions.

Clinical Details

Study design: Longitudinal, Convenience Sample, Prospective Study

Eligibility

Minimum age: 18 Years. Maximum age: 50 Years. Gender(s): Both.

Criteria:

Inclusion Criteria:

- Adult active duty personnel between 18 and 50 years of age with best corrected visual

acuity of 20/20 or better.

Exclusion Criteria:

- Patients not meeting above stated age criteria

- Females that are pregnant or lactating (non pregnant females of childbearing potential

will have pregnancy test prior to participating in study)

- History of serious ocular, neurological, cardiovascular disease

- History of severe systemic disease

- History of arrhythmias or high blood pressure

- Patients currently taking any type of ocular or systemic medications except

multivitamins.

- Patients with abnormal pupil shape, Addie's pupil, anisocoria, or abnormal pupil

defect.

Locations and Contacts

Walter Reed Army Medical Center, Washington, District of Columbia 20307, United States
Additional Information


Last updated: December 19, 2006

Page last updated: June 20, 2008

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