Bispectral Index Guiding Etomidate Used in Children Aged 3 to 10 for Clinical Anesthesia Induction
Information source: Henan Provincial Hospital
ClinicalTrials.gov processed this data on August 23, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Bispectral Index; Pediatric; Etomidate; Induction
Intervention: etomidate (Drug); propofol (Drug); sevoflurane (Drug)
Phase: Phase 4
Status: Not yet recruiting
Sponsored by: Henan Provincial Hospital Overall contact: Enqiang Chang, Email: clinicaltriallh@163.com
Summary
This research through using bispectral index to guide the induced dose and speed of
etomidate lipid emulsion for pediatric total venous anesthesia,and to provide a reference
for clinical anesthesia physician.
Clinical Details
Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Primary outcome: the amount of drugsthe drugs used time numbers of muscular fibrillation degree of inflammation reaction adrenal function
Secondary outcome: hemodynamic parameterssedation degree
Eligibility
Minimum age: 3 Years.
Maximum age: 10 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
1. obtain informed consent;
2. undergoing elective hypospadias repair surgery under general anesthesia;
3. American society of anesthesiologists (ASA) class I-II;
4. aged between 3-10 years old;
5. BMI is 18. 5-30 kg/m2;
Exclusion Criteria:
1. systolic blood pressure≥180 mmHg or<90 mmHg, diastolic blood pressure≥110 mmHg or<60
mmHg;
2. serious heart, brain, liver, kidney, lung, endocrine diseases or serious infections;
3. long-term use of hormone or a history of adrenal cortex inhibition;
4. suspected or confirmed difficult airway;
5. suspected or confirmed abuse of narcotic analgesic drugs, psychotropic drugs;
6. neuromuscular disease;
7. mental instability, or have a mental illness;
8. allergic to investigational products or with other contraindication
9. participated in other study within 30 days
Locations and Contacts
Enqiang Chang, Email: clinicaltriallh@163.com Additional Information
Starting date: October 2014
Last updated: July 2, 2014
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