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Cut-Off Progesterone Values Deleterious for In Vitro Fertilization and Fresh Embryo Transfer

Information source: Institut Universitari Dexeus
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Progesterone; Fertilization in Vitro; Infertility; Pregnancy

Intervention: Progesterone (Other)

Phase: N/A

Status: Completed

Sponsored by: Institut Universitari Dexeus


At which deleterious cut off value of progesterone on day of HCG (P-hCG) in our IVF program should fresh embryo transfer (ET) be cancelled?

Clinical Details

Official title: Cut-Off Progesterone Values Deleterious for In Vitro Fertilization and Fresh Embryo Transfer

Study design: Observational Model: Case-Crossover, Time Perspective: Retrospective

Primary outcome: Clinical Pregnancy

Detailed description: There is still an ongoing debate on the effect of subtle increased P-hCG concentration on pregnancy outcome after fresh ET. No consensus on the cut-off value to define increased P-hCG seems to exist. It is accepted that high P advances endometrium, leading to asynchrony between the implanting embryo and the endometrium, and resulting in implantation failure. A freeze all embryos policy and postponement of ET in subsequent frozen-thawed cycle has been proposed.


Minimum age: 18 Years. Maximum age: 49 Years. Gender(s): Female.


Inclusion Criteria:

- Fresh embryo transfer

- Progesterone value on day HCG (Human choriogonadotrophin hormone)

Exclusion Criteria:

- Clinical indication for delaying embryo transfer

Locations and Contacts

Additional Information

Starting date: January 2009
Last updated: December 22, 2014

Page last updated: August 23, 2015

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