Psoriasis Longitudinal Assessment and Registry (PSOLAR)

Condition(s) targeted: Psoriasis; Arthritis, Psoriatic

Phase: Phase 4

Status: Recruiting

Sponsored by: Centocor, Inc.

Official(s) and/or principal investigator(s):
Centocor, Inc. Clinical Trial, Study Director, Affiliation: Centocor, Inc.

Overall contact:
Use link at the bottom of the page to see if you qualify for an enrolling site (see list). If you still have questions:, Email: info1@veritasmedicine.com

The purpose of this study is to evaluate the safety of infliximab in patients with chronic severe plaque psoriasis as well as the clinical outcomes, quality of life and comorbidities for patients who receive conventional systemic or biologic therapy for plaque psoriasis.

Official title: A Multicenter, Open Registry of Patients With Plaque Psoriasis Who Are Candidates for Systemic Therapy Including Biologics

Study design: Prospective

Detailed description: Psolar is an 8-10 year registry study. A registry is an observational study that evaluates the status of a disease. This registry study will only include subjects who volunteer to take part. About 4000 infliximab-exposed subjects and 4000 additional patients receiving other Psoriasis medications/treatments (e. g. Etanercept, steroids, etc.) will take part in the registry study at about 450 centers in the U. S. The Registry does not require any study-specific testing, but may capture test information (e. g. laboratory tests, X-rays) that are collected as part of normal routine care for the registry program. Patient information will be collected at the enrollment visit and about every 6 months thereafter. Upon enrollment, the following information will be collected: demographics (e. g. gender, race, date of birth), medical history, family medical history, history of previous psoriasis treatments, current medications, how you receive infliximab or standard therapies and clinical follow-up, observations from your physical examinations, clinical disease status, Quality of life assessment (e. g. Dermatology Life Quality Index, Hospital Anxiety and Depression Scale, EQ-5D Health Questionnaire Scale, Employment/Productivity Health Economic

Questionnaire), current medications, and any adverse events/problems. During each six - month

follow-up visit with the study doctor, information collected will include observations from physical examination, updates on clinical disease status, Quality of life assessments, medications and adverse events/problems.

No study agents will be administered in this registry. All patients will receive standard of care treatments prescribed by the patient's physician.

Minimum age: 18 Years. Maximum age: N/A. Gender(s): Both.

Criteria:

Inclusion Criteria:

- Have a diagnosis of psoriasis

- Are candidates for or are currently receiving conventional systemic agents (eg, MTX,

acitretin, cyclosporine or systemic PUVA) or biologic therapy for psoriasis including those with chronic severe (extensive and/or disabling) plaque psoriasis who may be treated with infliximab

- Ability to understand and sign an informed consent form

- Are willing to participate in regular follow-up visits

Exclusion Criteria:

- Refuse to consent or are unwilling to respond to request for a long term information

within the required time frame

- Are participating or have already planned to participate in a clinical trial with

non-marketed investigational agents or are participating in a Centocor-sponsored clinical trial with marketed agents

Use link at the bottom of the page to see if you qualify for an enrolling site (see list). If you still have questions:, Email: info1@veritasmedicine.com

Birmingham, Alabama 35205, United States; Recruiting

Florence, Alabama 35630, United States; Recruiting

Birmingham, Alabama 35233, United States; Recruiting

Huntsville, Alabama 35801, United States; Recruiting

Phoenix, Arizona 85032, United States; Recruiting

Tucson, Arizona 85718, United States; Recruiting

Scottsdale, Arizona 85255, United States; Recruiting

Vallejo, California 94590, United States; Recruiting

Fresno, California 93720, United States; Recruiting

San Diego, California 92103, United States; Recruiting

Rolling Hills Estates, California 90274, United States; Recruiting

San Diego, California 92123, United States; Recruiting

Redding, California 96001, United States; Recruiting

Beverly Hills, California 90211, United States; Recruiting

San Ramon, California 94583, United States; Recruiting

Fresno, California 93710, United States; Recruiting

Sherman Oaks, California 91403, United States; Recruiting

Mountain View, California 94040, United States; Recruiting

Oxnard, California 93030, United States; Recruiting

Los Angeles, California 90045, United States; Recruiting

Garden Grove, California 92843, United States; Recruiting

Bridgeport, Connecticut 06606, United States; Recruiting

Wilmington, Delaware 19810, United States; Recruiting

Melbourne, Florida 32940, United States; Recruiting

Aventura, Florida 33180, United States; Recruiting

Seminole, Florida 33776, United States; Recruiting

North Miami Beach, Florida 33162, United States; Recruiting

Naples, Florida 34109, United States; Recruiting

Miami, Florida 33136, United States; Recruiting

Boynton Beach, Florida 33437, United States; Recruiting

Carrollton, Georgia 30117, United States; Recruiting

Alpharetta, Georgia 30022, United States; Recruiting

Rome, Georgia 30165, United States; Recruiting

Arlington Heights, Illinois 60005, United States; Recruiting

Champaign, Illinois 61820, United States; Recruiting

Lincolnshire, Illinois 60069, United States; Recruiting

Schaumburg, Illinois 60194, United States; Recruiting

West Dundee, Illinois 60118, United States; Recruiting

Skokie, Illinois 60077, United States; Recruiting

New Albany, Indiana 47150, United States; Recruiting

Indianapolis, Indiana 46256, United States; Recruiting

Indianapolis, Indiana 46260, United States; Recruiting

West Lafayette, Indiana 47906, United States; Recruiting

Plainfield, Indiana 46168, United States; Recruiting

Topeka, Kansas 66614, United States; Recruiting

Corbin, Kentucky 40701, United States; Recruiting

Catonsville, Maryland 21228, United States; Recruiting

Westminster, Maryland 21157, United States; Recruiting

Quincy, Massachusetts 02169, United States; Recruiting

Boston, Massachusetts 02111, United States; Recruiting

Clarkston, Michigan 48346, United States; Recruiting

Port Huron, Michigan 48060, United States; Recruiting

Flint, Michigan 48532, United States; Recruiting

Grand Blanc, Michigan 48439, United States; Recruiting

Troy, Michigan 48084, United States; Recruiting

Ann Arbor, Michigan 48103, United States; Recruiting

Clinton Twp, Michigan 48038, United States; Recruiting

Grand Rapids, Michigan 49503, United States; Recruiting

Minneapolis, Minnesota 55404, United States; Recruiting

Saint Louis, Missouri 63117, United States; Recruiting

Nashua, New Hampshire 03062, United States; Recruiting

Wyckoff, New Jersey 07481, United States; Recruiting

Hoboken, New Jersey 07030, United States; Recruiting

Rutherford, New Jersey 07070, United States; Recruiting

Marlton, New Jersey 08053, United States; Recruiting

East Windsor, New Jersey 08520, United States; Recruiting

Somerset, New Jersey 08873, United States; Recruiting

New York, New York 10016, United States; Recruiting

Suffern, New York 10901, United States; Recruiting

Williamsville, New York 14221, United States; Recruiting

New York, New York 10012, United States; Recruiting

Rochester, New York 00000, United States; Recruiting

Commack, New York 11725, United States; Recruiting

White Plains, New York 10604, United States; Recruiting

Staten Island, New York 10314, United States; Recruiting

Dayton, Ohio 45415, United States; Recruiting

Delaware, Ohio 43015, United States; Recruiting

Gahanna, Ohio 43230, United States; Recruiting

Dayton, Ohio 45408, United States; Recruiting

Portland, Oregon 97210, United States; Recruiting

Coos Bay, Oregon 97420, United States; Recruiting

Exton, Pennsylvania 19341, United States; Recruiting

Philadelphia, Pennsylvania 19103, United States; Recruiting

Pittsburgh, Pennsylvania 15213, United States; Recruiting

Spartanburg, South Carolina 29306, United States; Recruiting

Charleston, South Carolina 29414, United States; Recruiting

Piedmont, South Carolina 29673, United States; Recruiting

Fort Mill, South Carolina 29708, United States; Recruiting

Dallas, Texas 75231, United States; Recruiting

Arlington, Texas 76011, United States; Recruiting

Dallas, Texas 75237, United States; Recruiting

Longview, Texas 75605, United States; Recruiting

Dallas, Texas 75246, United States; Recruiting

Houston, Texas 77030, United States; Recruiting

Virginia Beach, Virginia 23454, United States; Recruiting

Arlington, Virginia 22204, United States; Recruiting

Richland, Washington 99352, United States; Recruiting

Seattle, Washington 98104, United States; Recruiting

Seattle, Washington 98101, United States; Recruiting

Dayton, Washington 99328, United States; Recruiting

To learn how to participate in this trial please click here.

Starting date: June 2007
Last updated: February 27, 2009