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The Effect of Nicardipine on Kidney Function During Orthognathic Surgery Under Hypotensive Anesthesia

Information source: Yonsei University
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Healthy Subjects

Intervention: Nicardipine (Drug); remifentanil (Drug)

Phase: N/A

Status: Completed

Sponsored by: Yonsei University

Official(s) and/or principal investigator(s):
Ji Young Kim, Principal Investigator, Affiliation: Severance hospital, YUHS


Since nicardipine is known to protect kidney function, nicardipine infusion will result in better renal parameters measured in this study.

Clinical Details

Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Prevention

Primary outcome: Creatinine Clearance


Minimum age: 20 Years. Maximum age: 40 Years. Gender(s): Both.


Inclusion Criteria:

- healthy adult patients undergoing hypotensive anesthesia

Exclusion Criteria:

- patients with any co-morbidity

Locations and Contacts

Additional Information

Starting date: August 2010
Last updated: June 11, 2013

Page last updated: August 23, 2015

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