Standard Medical Management in Secondary Prevention of Ischemic Stroke in China

Condition(s) targeted: Stroke

Intervention: Aspirin / Clopidogrel, Atorvastatin / Simvastatin (Drug); Asprin / Clopidogrel, Atorvastatin / Simvastatin (Drug)

Phase: N/A

Status: Recruiting

Sponsored by: Peking Union Medical College Hospital

Official(s) and/or principal investigator(s):
Liying Cui, Principal Investigator, Affiliation: Peking Union Medical College Hospital

Overall contact:
Liying Cui, Phone: 86-10-6529-6373, Email: pumchcly@yahoo.com.cn

The purposes of the study are to analyse the cross-section data of secondary stroke prevention in China and to carry out a standard medical management including medicine and interactive education program,and to evaluate the efficacy and safety of the standard medical management in secondary stroke prevention.

Official title: Standard Medical Management in Secondary Prevention of Ischemic Stroke in China.

Study design: Prevention, Randomized, Open Label, Active Control, Parallel Assignment, Safety/Efficacy Study

Primary outcome: Success Rate of standard medical management

Secondary outcome:

Ischemic stroke

Non-fatal acute coronary syndrome

Transient Ischemic Attack

Hemorrhagic Stroke

All-cause Death

Minimum age: 18 Years. Maximum age: N/A. Gender(s): Both.

Criteria:

Inclusion Criteria:

1. Ischemic cerebral infarction or TIA within 30 days.

2. Aged above 18 years old.

3. Hospitalized.

4. Cranial CT or MRI scan exclude intracranial hemorrhagic diseases

5. Stable clinical and neurological conditions.

6. A Modified Rankin score less than 4 at enrollment

7. Informed consent is obtained.

Exclusion Criteria:

Patients will be excluded from entry if any of the criteria listed below are met

1. Documented stroke caused by conditions other than atherosclerosis, ie, surgical or vascular intervention procedure.

2. Severe co-morbid or unstable medical condition, ie, heart failure, respiratory failure and renal failure, severe liver dysfunction, malignancy with likelihood of death within the next 2 years

3. Significant memory or behavioural disorder, ie, Alzheimer disease, etc, daily care needed.

4. A Modified Rankin score is more than 4

5. Concurrent participation in another clinical trial

6. Pregnant

7. Unable to give informed consent.

Liying Cui, Phone: 86-10-6529-6373, Email: pumchcly@yahoo.com.cn

China Pla General Hospital, Beijing 100853, China; Recruiting
Chenglin Tian, Email: tianchenglin719@yahoo.com.cn

Beijing Tiantan Hospital, Beijing, China; Recruiting
Yong Zhou, Email: yongzhou78214@163.com

Xuanwu Hospital Capital Medical University, Beijing, China; Recruiting
Jianping Jia, Email: jiajp@vip.sina.com

Peking University Third Hospital, Beijing, China; Recruiting
Jun Zhang, Email: Who626@163.com

China Rehabilition Research Center, Beijing, China; Recruiting
Jun Zhao, Email: zaojun@sohu.com

Beijing Shijitan Hospital, Beijing, China; Recruiting
Huiwen Xu, Email: xhwdoctor@163.com

Beijing Ji Shui Tan Hospital,the 4TH Medical College of Peking University, Beijing, China; Recruiting
Yuheng Sun, Email: yuhengs@126.com

Beijing Daxing District Hospital, Beijing, China; Recruiting
Liuzhuang Zhao, Email: Zlz66@yahoo.com.cn

Luhe Hospital of Tongzhou Distict Beijing, Beijing, China; Recruiting
Huishan Du, Email: smashxk@msn.com

General Hospital of Navy, Beijing, China; Recruiting
Xiaokun Qi, Email: bjqxk@sina.com

No 263 Hospital of Pla, Beijing, China; Recruiting
Jinli Zhang, Email: hi1044@163.com

No 309 Hospital of Pla, Beijing, China; Recruiting
Yuping Chen, Email: leafcyp@163.com

Pinggu County Hospital Beijing, Beijing, China; Recruiting
Guiyun Zhang, Email: pgzhangguiyun@2008.sina.com

Peking Union Medical College Hosptial, Beijing 100730, China; Recruiting
Liying Cui, Phone: 86-10-65296373, Email: pumchcly@yahoo.com.cn
Bin Peng, Phone: 86-10-65296371, Email: pengbin3@hotmail.com

Daping Hospital, Chongqing, China; Recruiting
Huadong Zhou, Email: Zhouhuadong@163.com

Southwest Hospital, Chongqing, China; Recruiting
Shugui Shi, Email: southwestneuro@163.com

Shanghai Changzheng Hospital, Shanghai, China; Recruiting
Xiaoyan Chen, Email: abilitywin@163.com

Huashan Hospital Fudan University, Shanghai, China; Recruiting
Liang Wang, Email: autum88_cn@yahoo.com

the General Hospital Under Tianjin Medical Sciences University, Tianjin, China; Recruiting
Yan Cheng, Email: cylfl@sohu.com

Tianjin Third Central Hospital, Tianjin, China; Recruiting
Zhecheng Zhang, Email: zzc0912@yahoo.com.cn

Guangzhou First Municipal People's Hospital, Guangzhou, Guangdong, China; Recruiting
Mengyan Li

the First Affiliated Hospital,Sun Yat-sen Unversity, Guangzhou, Guangdong, China; Recruiting
Hua Hong, Email: hhsums@163.com

Hebei North University, Zhangjiakou, Hebei, China; Recruiting
Shumin Yue, Email: yuesm6903@sina.com

the Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China; Recruiting
Zhenzhong Li, Email: johndoctor@126.com

Yutian County Hospital, Yutian, Hebei, China; Recruiting
Jinchao Wang, Phone: 86-0315-6158126

the First Hospital of Hebei Medical University, Shijiazhuang, Hebei, China; Recruiting
Mingwei Wang, Email: wmw@hebmu.edu.cn

the Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, China; Recruiting
Junyan Liu, Email: junyanliu2003@yahoo.com.cn

the First Hospital of Harbin Medical University, Harbin, Helongjiang, China; Recruiting
Weizhi Wang, Email: wwz_h2008@yahoo.com.cn

the Second Hospital of Harbin Medical University, Harbin, Helongjiang, China; Recruiting
Liming Zhang, Email: zfx001@yahoo.com

Henan Provincial People's Hospital, Zhengzhou, Henan, China; Recruiting
Jiewen Zhang, Email: zhangjiewen9900@126.com

the Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Recruiting
Junjian Zhang, Email: wdsjkx@yahoo.com.cn

Xiangya Hospital of Centre-south University, Changsha, Hunan, China; Recruiting
Jian Xia, Email: xiajian1216@sina.com

Inner Mongolia Baotou City Central Hospital, Baotou, Inner Mongolia, China; Recruiting
Jingfen Zhang, Email: zhangjingfen@263.sina.com

the Appurtenant Hospital of Chifeng University, Chifeng, Inner Mongolia, China; Recruiting
Qifu Cui, Email: Cxb1986@sina.com

Jiangsu Province Hospital, Nanjing, Jiangsu, China; Recruiting
Xinsheng Ding, Email: xsding@publicl.ptt.js.cn

the Affiliated Drumtower Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China; Recruiting
Yun Xu, Email: xuyun20042001@yahoo.com.cn

Nanjing General Hospital of Nanjing Military Command, Nanjing, Jiangsu, China; Recruiting
Gelin Xu, Email: gelinxu@gmail.com

Jilin University, Changchun, Jilin, China; Recruiting
Jiang Wu, Email: sjnkwujing@sina.com

the First Affiliated Hospital of China Medical Sciences University, Shenyang, Liaoning, China; Recruiting
Chaodong Zhang, Email: xczhang@163.com

the Third People's Hospital of Dalian, Dalian, Liaoning, China; Recruiting
Jingbo Zhang, Email: dlzhangjingbo@163.com

Qinghai Provincial People's Hospital, Xining, Qinghai, China; Recruiting
Jinpeng Wang, Email: qhwjp@yahoo.com.cn

Qilu Hospital of Shangdong University, Jinan, Shandong, China; Recruiting
Shuzhen Wang, Email: xxwsz63@yahoo.com.cn

the Second Hospitalof Shangdong University, Jinan, Shandong, China; Recruiting
Wei Shang, Email: wshang85@yahoo.com.cn

West China Center of Medical Sciences, Chengdu, Sichuan, China; Recruiting
Dong Zhou, Email: zhoudong66@yahoo.de

First Affiliated Hospital of Xinjiang Medical University, Uramuqi, Xinjiang uygur autonomous region, China; Recruiting
Xiaoning Zhang, Email: zxn-1960@163.com

the First Affiliated Hospital of College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Recruiting
Jianwen Wang, Email: warrington@126.com

Starting date: April 2008
Ending date: August 2010
Last updated: September 16, 2009