DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more



Efficacy of Pre-operative Oral Pregabalin in Ambulatory Inguinal Hernia Repair for Post Operative Pain

Information source: University of Malaya
ClinicalTrials.gov processed this data on November 27, 2014
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Inguinal Hernia; Postoperative Pain

Intervention: Pregabalin (Drug)

Phase: Phase 3

Status: Recruiting

Sponsored by: University of Malaya

Official(s) and/or principal investigator(s):
CharngChee Toh, MBBS, MRCS, Principal Investigator, Affiliation: University Malaya

Overall contact:
CharngChee Toh, MBBS, MRCS, Phone: 60193380337, Email: toh2c79@yahoo.com

Summary

The study carry out is to determine whether the use of oral pregabalin premedication to assess the analgesic efficacy, opiod sparing, adverse effect and clinical value in post-operative pain management.

Clinical Details

Official title: Efficacy of Pre-operative Oral Pregabalin in Ambulatory Inguinal Hernia Repair for Post Operative Pain

Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Primary outcome: Study is constructed to determine whether the use of oral pregabalin premedication to assess the analgesic efficacy for post operative pain at Alert, 15, 30, 45, 60 and 120 min, Day 1, Day 2 and Day 3.

Secondary outcome:

Opiod Sparing

Side effect of medication

Eligibility

Minimum age: 12 Years. Maximum age: 75 Years. Gender(s): Both.

Criteria:

Inclusion Criteria:

- Clinical diagnosis of inguinal hernia

- Patient undergo operation under daycare basis

- ASA I-II

- Written consent

Exclusion Criteria:

- ASA > II

- Allergic reaction against gabapentin and/or pregabalin

- History of recurrent hernia repair.

- Patient who has taken analgesia prior to the surgery

- Liver failure

- Renal failure

- Pregnancy

Locations and Contacts

CharngChee Toh, MBBS, MRCS, Phone: 60193380337, Email: toh2c79@yahoo.com

University Malaya, Kuala Lumpur 59100, Malaysia; Recruiting
CharngChee Toh, MBBS, MRCS, Phone: 60193380337, Email: toh2c79@yahoo.com
CharngChee Toh, MBBS, MRCS, Principal Investigator
Additional Information

Starting date: September 2009
Last updated: October 11, 2011

Page last updated: November 27, 2014

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2014