Adrenal Scans With Radioiodine-Labeled Norcholesterol (NP-59)
Information source: Memorial Sloan Kettering Cancer Center
ClinicalTrials.gov processed this data on August 20, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Adrenal Tumors; Adrenal Malignancies; Abnormal Hormonal Secretions; Electrolytes Abnormalities
Intervention: Imaging, Adrenal acans (Procedure); (NP-59) (Radiation)
Phase: N/A
Status: Completed
Sponsored by: Memorial Sloan Kettering Cancer Center Official(s) and/or principal investigator(s): Neeta Pandit-Taskar, MD, Principal Investigator, Affiliation: Memorial Sloan Kettering Cancer Center
Summary
The purpose of this study is to find out if your adrenal glands are normal or abnormal. This
can be determined by whether or not your adrenal gland concentrates more of a labeled
building block of adrenal hormone, norcholesterol. This labeled material had been used as an
investigative diagnostic tool for imaging adrenal glands for many years with success in our
hands. This is a diagnostic procedure. CT, MRI and Ultrasound can determine the size and
presence or absence of tumor but cannot assess the function of the adrenal glands. To
determine hormone concentrations from blood samples would involve more invasive
catherization.
Clinical Details
Official title: Adrenal Scans With Radioiodine-Labeled Norcholesterol (NP-59)
Study design: Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
Primary outcome: To investigate the feasibility of using NP-59 to localize adrenal tumors and assess their functions under the influence of pharmacological manipulations.
Detailed description:
To investigate the feasibility of using NP-59 to localize adrenal tumors and assess their
functions under the influence of pharmacological manipulations.
Eligibility
Minimum age: N/A.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Patient with clinical and laboratory suspicions of hypersecretion of adrenal cortical
hormones
Exclusion Criteria:
- n/a
Locations and Contacts
Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States
Additional Information
Memorial Sloan Kettering web site
Starting date: July 1977
Last updated: April 29, 2015
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