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Adrenal Scans With Radioiodine-Labeled Norcholesterol (NP-59)

Information source: Memorial Sloan-Kettering Cancer Center
Information obtained from ClinicalTrials.gov on October 19, 2009
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Adrenal Tumors; Adrenal Malignancies; Abnormal Hormonal Secretions; Electrolytes Abnormalities

Intervention: Imaging, Adrenal acans (Other)

Phase: N/A

Status: Recruiting

Sponsored by: Memorial Sloan-Kettering Cancer Center

Official(s) and/or principal investigator(s):
Neeta Pandit-Taskar, MD, Principal Investigator, Affiliation: Memorial Sloan-Kettering Cancer Center

Overall contact:
Neeta Pandit-Taskar, MD, Email: pandit-n@mskcc.org

Summary

The purpose of this study is to find out if your adrenal glands are normal or abnormal. This can be determined by whether or not your adrenal gland concentrates more of a labeled building block of adrenal hormone, norcholesterol. This labeled material had been used as an investigative diagnostic tool for imaging adrenal glands for many years with success in our hands. This is a diagnostic procedure. CT, MRI and Ultrasound can determine the size and presence or absence of tumor but cannot assess the function of the adrenal glands. To determine hormone concentrations from blood samples would involve more invasive catherization.

Clinical Details

Official title: Adrenal Scans With Radioiodine-Labeled Norcholesterol (NP-59)

Study design: Diagnostic, Open Label, Single Group Assignment, Efficacy Study

Primary outcome: To investigate the feasibility of using NP-59 to localize adrenal tumors and assess their functions under the influence of pharmacological manipulations.

Detailed description: To investigate the feasibility of using NP-59 to localize adrenal tumors and assess their functions under the influence of pharmacological manipulations.

Eligibility

Minimum age: N/A. Maximum age: N/A. Gender(s): Both.

Criteria:

Inclusion Criteria:

- Patient with clinical and laboratory suspicions of hypersecretion of adrenal cortical

hormones

Exclusion Criteria:

- n/a

Locations and Contacts

Neeta Pandit-Taskar, MD, Email: pandit-n@mskcc.org

Memorial Sloan-Kettering Cancer Center, New York, New York 10065, United States; Recruiting
Neeta Pandit-Taskar, MD, Email: pandit-n@mskcc.org
Additional Information

Memorial Sloan-Kettering web site

Starting date: July 1977
Ending date: December 2010
Last updated: June 19, 2009

Page last updated: October 19, 2009

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