DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more



Comparison of Pantoprazole and Ranitidine in Dyspepsia

Information source: Akdeniz University
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Dyspepsia

Intervention: Pantoprazole (Drug); Ranitidine (Drug)

Phase: Phase 4

Status: Completed

Sponsored by: Akdeniz University

Official(s) and/or principal investigator(s):
Cenker Eken, Proffesor, Study Director, Affiliation: Akdeniz University

Summary

The H0 hypothesis of the study is there is no difference between pantoprazole and ranitidine in treating patients presented with dyspepsia to the emergency department. The H1 hypothesis is there is difference between pantoprazole and ranitidine in treating patients presented with dyspepsia to the emergency department.

Clinical Details

Official title: Intravenous Pantoprazole vs Ranitidine in Dyspepsia in Emergency Department: A Randomized Controlled Trial.

Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Primary outcome: Visual Analogue Scale Score

Secondary outcome: Need for Additional Drug

Detailed description: Dyspepsia is one of the common complaints in emergency department. Proton pomp inhibitors, H2 receptor blockers and anti-acids are common drugs for treating dyspepsia in emergency department. However there is no study in the emergency department comparing the effectiveness of these drugs. So the investigators planned this study which drug is effective in these patients in order to provide a cost-effective treatment in dyspeptic patients.

Eligibility

Minimum age: 18 Years. Maximum age: N/A. Gender(s): Both.

Criteria:

Inclusion Criteria:

- Epigastric pain

- Older than 18 years old

Exclusion Criteria:

- Diagnosed as cholecystitis, pancreatitis, myocardial infarction, etc.. at the end of

the emergency deparment evaluation period.

- Pregnancy

- Patients with unstable vital signs

- Patients used anti-acid, H2 receptor blockers and proton pomp inhibitors in the last

one hour.

- Allergy to H2 receptor blockers and proton pomp inhibitors.

- Patients denied to give inform consent and who are illiterate

Locations and Contacts

Akdeniz University, Antalya 07050, Turkey
Additional Information

The web adress of the organization which this study is conducted.

Related publications:

Welling LR, Watson WA. The emergency department treatment of dyspepsia with antacids and oral lidocaine. Ann Emerg Med. 1990 Jul;19(7):785-8.

Starting date: October 2012
Last updated: June 27, 2015

Page last updated: August 23, 2015

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017