The purpose of this study is to collect epidemiological data in children and adolescents
with chronic hepatitis B(CHB), in particular data on the prevalence of HBeAg positive
disease with associated ALT levels , active HBeAg negative disease and decompensated CHB in
the pediatric population. Family history and history of HBV transmission is essential to
assess the course of the disease and can be used to determine the best mode of treatment
This information will be used to assist with the feasibility and design of studies for the
Novartis clinical pediatric development program, as the current epidemiology of ediatric CHB
is not accurately known in Western countries or the rest of the world making pediatric
studies difficult to plan and conduct. This study forms part of the Novartis Pediatric
Investigational Plan, a post marketing approval commitment to the EMEA Pediatric Committee.
Hospital de Niños Dr. Ricardo Gutierrez, Capital Federal, Buenos Aires C1425EFD, Argentina
Hospital de Clínicas de Porto Alegre, Porto, Alegre 90035-903, Brazil
Núcleo de Estudos e Pesquisas em Hepatologia da Amazônia, Belém 66035-080, Brazil
Hospital Oswaldo Cruz - Universidade de Pernambuco, Recife 50100-130, Brazil
Instituto da Criança - HC FMUSP, São Paulo 05403-900, Brazil
Universidade de Campinas, Campinas, São Paulo 13083-887, Brazil
Beijing You'an Hosptial, Beijing 100069, China
1st Affliated Hospital of 3rd Military Med. Univ. of PLA, Chongqing 400038, China
The First Affiliated Hospital of Chongqing Med. University, Chongqing 400016, China
Hebei Medical University The Third Hospital, Shijiazhuang, Hebei 050051, China
Henan Academy of Medical Pharmaceutical Sciences, Zhengzhou, Henan 450052, China
Prince of Wales Hospital, Hong Kong, China
Queen Mary Hospital, Hong Kong, China
The Second Xiangya Hospital, Changsha, Hunan 410011, China
The Third Xiangya Hospital of Central South University, Changsha, Hunan 410013, China
Jiangsu Province Hospital, Nanjing, Jiangsu 210029, China
First Hospital University of Jilin, Changchun, Jilin 130021, China
The First Affiliated Hospital of Medical College, Kunming, Kunming 650032, China
The First Affiliated Hospital of Lanzhou University, Lanzhou 730000, China
The First Affiliated Hospital of Soochow University, Suzhou 215006, China
Institute of Hematol., Union Hospital, Tongji Med. College, Wuhan 430022, China
Second Hospital of Xian Jiaotong University, Xi'an 710004, China
Hospital of Chengdu Military Area Command, Kunming, Yunnan 650032, China
Groupe Hospitalier Pellegrin - Hôpital des Enfants, Bordeaux, Aquitaine 33076, France
Hôpital Jeanne de Flandre, Lille 59037, France
Groupe Hospitalier Necker - Enfants Malades, Paris 75015, France
Hôpital de Haute Pierre, Strasbourg 67098, France
Peripheral University General Hospital of Alexandroupoli, Alexandroupolis 68100, Greece
"Agia Sofia" Childrens Hospital of Athens, Athens 11527, Greece
IASO Children's Hospital, Athens 15123, Greece
University General Hospital of Heraklion, Heraklion, Crete 71110, Greece
Childrens' General Hospital of Athens 'P&A Kyriakou', Goudi 11527, Greece
Dr. R. K. Jain Clinic, Bhopal 462016, India
Choithram Hospital and Research Centre, Indore 452014, India
St. John's Medical College Hospital, Banglaore, Karna 560034, India
Apollo Gleneagles Hospital, Kolkata 700054, India
TNMC and BYL Nair Charitable Hospital, Mumbai 400008, India
Maulana Azad Medical College & LNJP Hospital, New Delhi 110002, India
Azienda Osp.-Univ. Bologna - Policlinico S.Orsola-Malpighi, Bologna 40138, Italy
Istituto G. Gaslini Ospedale Pediatrico IRCCS, Genova 16147, Italy
Universita degli Studi "Federico II", Napoli 80131, Italy
Azienda Ospedaliero Universitaria Pisana, Pisa 56123, Italy
Ospedale Pediatrico Bambino Gesu, Roma 00165, Italy
Hospital Nacional Edgardo Rebagliati Martins, Lima 11, Peru
Hospital Nacional G A Yrigoyen, Lima 13, Peru
Instituto Nacional de Salud del Niño, Lima LI33, Peru
Philippine General Hospital, Ermita 1000, Philippines
Research Institute for Tropical Medicine, Muntinlupa City 1781, Philippines
National Kidney and Transplant Institute, Quezon City 1104, Philippines
Philippine Children's Medical Center, Quezon City 1100, Philippines
Wojewodzki Spital Bydgoszcz, Bydgoszcz 85-030, Poland
Krakowski Szpital Specjalistyczny im. Jana Pawla II, Krakow 31-202, Poland
Instytut Centrum Zdrowia Matki Polki, Lodz 93-338, Poland
"Matei Bals" Institute of Infectious Diseases, Bucharest 021105, Romania
Fundeni Clinical Institute, Bucharest 022328, Romania
V. Babes Pneumology and Infectious Diseases Clin. Hosp, Craiova 200515, Romania
Central Research Institute for Epidemiology of Rospotrebnadz, Moscow 11123, Russian Federation
Research Center of Children's Health, Moscow 119991, Russian Federation
Russian State Medical University, Moscow 117049, Russian Federation
Saint- Petersburg State Mtchnikov's Medical Academy, Saint Petersburg 194100, Russian Federation
Smolensk State Medical Academy, Smolensk 214019, Russian Federation
Research Institute for Infectious Childhood Diseases, St. Petersburg 197022, Russian Federation
KK Women's and Children's Hospital, Singapore 229899, Singapore
National University of Singapore, Singapore 119074, Singapore
Hospital Universitario San Cecilio, Granada, Andalucía 18012, Spain
Hospital Sant Joan de Deu, Barcelona, Cataluña 08950, Spain
Hospital Carlos III, Madrid 28029, Spain
Hospital Universitario de Getafe, Madrid 28905, Spain
Hospital Universitario La Paz, Madrid 28046, Spain
Hospital Universitario La Fe, Valencia 46009, Spain
Chung Shan Medical University Hospital, Taichung 402, Taiwan
Taichung Veteran's General Hospital, Taichung 40705, Taiwan
Cathay General Hospital, Taipei 10650, Taiwan
National Taiwan University Hospital, Taipei 100, Taiwan
Ramathibodi Hospital, Bangkok 10400, Thailand
Maharaj Nakorn Chiangmai Hospital, Chiang Mai 50200, Thailand
Birmingham Childrens Hospital, Birmingham B46NH, United Kingdom
St James's University Hospital, Leeds LS97TF, United Kingdom
Kings College Hospital, London SE5 9RS, United Kingdom
The Royal London Hospital, London E12AT, United Kingdom
Queen's Medical Centre, Nottingham NG72UH, United Kingdom
The Children's Hospital, Aurora, Colorado 80045, United States
Shands Hospital at University of Florida, Gainesville, Florida 32610, United States
Children's Hospital Boston, Boston, Massachusetts 02115, United States
Saint Vincent Healthcare Pediatric Specialty Clinics, Billings, Montana 59101, United States
The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, United States
