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Bryophyllum vs. Nifedipine

Information source: Weleda AG
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Tocolysis

Intervention: Bryophyllum p. (Drug)

Phase: Phase 2/Phase 3

Status: Not yet recruiting

Sponsored by: Weleda AG

Official(s) and/or principal investigator(s):
Roland Zimmermann, Prof. Dr. med., Principal Investigator, Affiliation: Department of Obstetrics, University Zuerich


In a prospective, randomised study the efficacy and tolerability of bryophyllum p. (p. o) vs. nifedipine (p. o) will be proofed in a defined group of pregnant women with threatened preterm labour.

Clinical Details

Official title: Bryophyllum p. Versus Nifedipine for the Treatment of Premature Contractions

Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment


Minimum age: 18 Years. Maximum age: 45 Years. Gender(s): Female.


Inclusion Criteria:

- Female

Exclusion Criteria:

- Bishop Score > 5

Locations and Contacts

Department of Obstetrics, University of Zuerich, Zuerich 8091, Switzerland; Not yet recruiting
Roland Zimmermann, Prof. Dr. med., Principal Investigator
Ursula von Mandach, Prof. Dr. pharm., Principal Investigator
Additional Information

Related publications:

Plangger N, Rist L, Zimmermann R, von Mandach U. Intravenous tocolysis with Bryophyllum pinnatum is better tolerated than beta-agonist application. Eur J Obstet Gynecol Reprod Biol. 2006 Feb 1;124(2):168-72. Epub 2005 Jul 26.

Gwehenberger B, Rist L, Huch R, von Mandach U. Effect of Bryophyllum pinnatum versus fenoterol on uterine contractility. Eur J Obstet Gynecol Reprod Biol. 2004 Apr 15;113(2):164-71.

VilĂ ghy I. [Decreasing the rate of premature delivery with phytotherapy--results from general practice]. Ther Umsch. 2002 Dec;59(12):696-701. German.

Starting date: November 2006
Last updated: October 19, 2006

Page last updated: August 23, 2015

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