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Metabolic Changes in Hypothyroid Patients

Information source: University of Aarhus
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Hypothyroidism

Intervention: L-thyroxine (Drug)

Phase: N/A

Status: Completed

Sponsored by: University of Aarhus

Official(s) and/or principal investigator(s):
Signe Gjedde, MD, Principal Investigator, Affiliation: Aarhus University, Clinical Institute


Hypothyroidism is a frequent condition in danish women, but often overlooked. Along with fatigue one of the main symptoms is weight gain as a result to significantly decreased energy expenditure. This study was undertaken to elucidate changes in glucose, lipid and amino acid turnover in these patients.

Clinical Details

Official title: Impact of Hypothyroidism on Glucose, Lipid, and Amino Acid Turnover

Study design: Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science


Minimum age: 18 Years. Maximum age: N/A. Gender(s): Both.


Inclusion Criteria:

- Newly diagnosed hypothyroidism with tsh over 40 mU/L, etiology chronic autoimmune


- Healthy controls matched regarding sex, age and body mass index

Exclusion Criteria:

- Pregnancy, breastfeeding

Locations and Contacts

Aarhus University Hospital, Aarhus 8000, Denmark
Additional Information

Starting date: March 2004
Last updated: February 7, 2008

Page last updated: August 23, 2015

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