Effect of Pre-injection of Lidocaine on Myoclonus Induced by Induction With Etomidate in Elderly Patients During General Anesthesia
Information source: Tang-Du Hospital
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: General Anesthesia
Intervention: Lidocaine Hydrochloride Injection (Drug); Etomidate Fat Emulsion Injection (Drug); normal saline (Drug); Midazolam Injection (Drug); Fentanyl Citrate Injection (Drug); Rocuronium Injection (Drug)
Phase: Phase 4
Status: Recruiting
Sponsored by: Tang-Du Hospital Overall contact:
Yu Guo, Phone: +86-18009200936, Email: guoyu986121@163.com
Summary
To evaluate the effect of pre-injection of lidocaine on myoclonus induced by induction with
etomidate during general anesthesia in elderly patients
Clinical Details
Official title: Effect of Pre-injection of Lidocaine on Myoclonus Induced by Induction With Etomidate in Elderly Patients During General Anesthesia
Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
Primary outcome: severity of myoclonus induced byintensity of injection pain
Secondary outcome: hemodynamic parameters after injection of etomidate
Eligibility
Minimum age: 60 Years.
Maximum age: 81 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- 1. Aged between 60 and 81 years 2. Body mass index: 20 to 30 kg/m2 3. American
Society of Anesthesiology (ASA) Physical Status: Ⅰ or Ⅱ 4. Signed informed consent
form
Exclusion Criteria:
- 1. Use of sedatives or opioids 2. History of central nervous system diseases, like
epilepsy, shaking palsy, or chorea, etc 3. Hyperthyroidism 4. Serious diabetes 5.
Hyperkalemia 6. Cardiac surgery 7. Serious ventricular disease or atrioventricular
block 8. Liver or renal dysfunction 9. Allergies to amide local anesthetics or fat
emulsion
Locations and Contacts
Yu Guo, Phone: +86-18009200936, Email: guoyu986121@163.com
TangDu Hospital,FMMU, Xi'an, Shanxi, China; Recruiting
Yu Guo, Phone: +86-18009200936, Email: guoyu986121@163.com
Yu Guo, Principal Investigator
Additional Information
Starting date: May 2014
Last updated: May 16, 2014
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