Calcium, Dairy, and Body Fat in Adolescents
Information source: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
ClinicalTrials.gov processed this data on August 20, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Obesity; Energy Metabolism
Intervention: C (smoothies based on soy protein containing no additional calcium) (Dietary Supplement); B (smoothies based on soy protein containing calcium) (Dietary Supplement); A (smoothies based on dairy protein containing calcium) (Dietary Supplement)
Phase: N/A
Status: Completed
Sponsored by: Purdue University Official(s) and/or principal investigator(s): Connie Weaver, PHD, Principal Investigator, Affiliation: Department Foods and Nutrition, Purdue University Berdine R Martin, PhD, Study Director, Affiliation: Department Foods and Nutrition, Purdue University
Summary
Lifestyle choices,including diet,are conducive to healthy body weights in children. Dairy
products and calcium supplementation have been associated with moderation of body weight and
body fat. This study was designed to test the following hypotheses with overweight and obese
adolescents consuming a controlled diet:
- Dietary calcium supplementation as calcium carbonate or dairy calcium modulates energy
balance in adolescents.
- Increased calcium in the diet of adolescents will increase fecal fat excretion and
thereby decrease fat absorption.
- Calcium and dairy product supplementation will increase lipid oxidation resulting in an
increase in energy expenditure.
Clinical Details
Official title: Calcium, Dairy, and Body Fat in Adolescents
Study design: Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Outcomes Assessor), Primary Purpose: Treatment
Primary outcome: Energy balance will be calculated by quantitating the kilocalories represented by the following components: dietary intake, excreta, physical activity, resting energy expenditure, thermic effect of food, and thermogenesis.
Secondary outcome: Serum biochemical measures of calcium metabolism (PTH, Vitamin D, and calcium)Calcium retention
Detailed description:
Subjects will consume a controlled diet containing 800 mg calcium for two three week
periods. During one period they will also receive a frozen ice cream like product (smoothie)
twice a day based on soy protein that contains no additional calcium. During the other
period they will receive a similar product twice a day based on either dairy protein that
contains 650 mg calcium or based on soy protein that contains 650 mg calcium as calcium
carbonate
Eligibility
Minimum age: 12 Years.
Maximum age: 15 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Over weight (>85th percentile BMI for age)
Exclusion Criteria:
- > 180% of ideal body weight for height
- Malabsorptive disorders
- Bone disease
- Liver disease
- Kidney disease
- Anemia
- Smoking or illegal drugs
- Oral contraceptives
- Pregnancy
- Medications that influence calcium metabolism
Locations and Contacts
Department of Foods and Nutrition, W. Lafayette, Indiana 47907, United States
Additional Information
Starting date: April 2004
Last updated: January 12, 2010
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