Pre-operative Evaluation of Kidney & Pancreas Transplant Patients
Information source: University of Nebraska
Information obtained from ClinicalTrials.gov on October 19, 2009
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Kidney Transplantation; Pancreas Transplantation
Intervention: Dobutamine Stress Echocardiogram (Procedure)
Phase: N/A
Status: Recruiting
Sponsored by: University of Nebraska Official(s) and/or principal investigator(s):
Thomas R Porter, MD, Principal Investigator, Affiliation: University of Nebraska
Overall contact:
Thomas R Porter, MD, Phone: 402-559-7977, Email: trporter@unmc.edu
Summary
Examine the clinical utility of the dobutamine stress contrast echoes and angiograms
obtained routinely in the evaluation of patients prior to kidney or pancreas
transplantation.
Clinical Details
Official title: The Analysis of Data Collected During Angiography and Dobutamine Stress Contrast Echocardiograms in the Pre-Evaluation of Kidney and Pancreas Transplant Patients
Study design: Diagnostic, Open Label, Single Group Assignment
Primary outcome: Provide a higher sensitivity required to adequately assess risks in the pancreas/ kidney transplant evaluation
Secondary outcome: Eliminate the need for costly and invasive additional procedures
Detailed description:
Although there is an increasing quantity of data demonstrating the value of stress echo in
risk stratifying patients for cardiac risk prior to major non-cardiac surgery, the current
clinical practice utilized for assessing patients being evaluated for kidney or pancreas
transplantation is both a stress echocardiogram and a coronary angiogram. This gap in
opinion appears to be a concern on the part of both nephrologists, endocrinologists, and
surgeons that the stress echocardiogram may miss significant angiographic disease that could
result in major post-operative complications in this high-risk subgroup of patients
(unstable angina, non-fatal infarction, or death).
Eligibility
Minimum age: 19 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Patients who are being evaluated for a kidney and or pancreas transplant and
scheduled for a dobutamine stress echocardiogram and a coronary angiogram will be
eligible to participate
Exclusion Criteria:
- Patients with unstable angina at the time of their evaluation, or who have a severe
underlying cardiomyopathy or valve disease will be excluded.
Locations and Contacts
Thomas R Porter, MD, Phone: 402-559-7977, Email: trporter@unmc.edu
University of Nebraska Medical Center, Omaha, Nebraska 68105, United States; Recruiting
Saritha Dodla, MD, Phone: 402-559-7271, Email: sdodla@unmc.edu
Stacey L Kearney, BS, Phone: 402-559-7977, Email: skearney@unmc.edu
Thomas R Porter, MD, Principal Investigator
Additional Information
Starting date: April 2003
Ending date: April 2012
Last updated: August 5, 2009
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