Steroids After Laser Trabeculoplasty for Glaucoma

Condition(s) targeted: Glaucoma

Intervention: Prednisolone 1% (Drug); Diclofenac 0.1% (Drug); Artificial Tears (Drug)

Phase: Phase 4

Status: Recruiting

Sponsored by: University of Miami

The purpose of this study is to determine whether the choice of post-operative eye drop administered after selective laser trabeculoplasty (SLT) for glaucoma affects the efficacy in lowering intraocular pressure (IOP).

Official title: Steroids And Laser Trabeculoplasty (SALT) Trial: Effect of Anti-Inflammatory Treatment on the Efficacy of SLT

Study design: Treatment, Randomized, Double Blind (Subject, Caregiver, Investigator), Parallel Assignment, Safety/Efficacy Study

Primary outcome: Intraocular pressure lowering

Secondary outcome: Intraocular inflammation

Detailed description: SLT is used to lower intraocular pressure in glaucoma, but it is not know whether the choice of eyedrops administered in the post-operative period affects SLT efficacy. Practitioners commonly use steroid drops, non-steroidal anti-inflammatory drops, or no drops at all. This is a randomized, single-center, prospective, masked clinical trial to determine whether the choice of eyedrop affects efficacy of SLT in glaucoma patients.

Minimum age: 18 Years. Maximum age: N/A. Gender(s): Both.

Criteria:

Inclusion Criteria:

- clinical diagnosis of glaucoma

- clinician has determined that SLT laser is indicated

- IOP currently >18 and was ever >21 in the past (e. g. prior to treatment)

Exclusion Criteria:

- prior history of uveitis

- prior glaucoma surgery including glaucoma laser surgery

- pregnant or 3 months post-partum

Bascom Palmer Eye Institute, Miami, Florida 33136, United States; Recruiting
Jeffrey L. Goldberg, MD, PhD, Phone: 305-547-3720, Email: BascomPalmerEyeTrials@gmail.com
Jeffrey L Goldberg, MD, PhD, Principal Investigator

Starting date: September 2009
Ending date: March 2011
Last updated: September 21, 2009