Does Administration of Etomidate and Propofol of the Anesthetic Induction of Elderly Hypertensive Patient Provide Superior Blood Pressure Stability in Response to Direct Laryngoscopy When Compared to Propofol or Etomidate Alone?
Information source: University of Mississippi Medical Center
ClinicalTrials.gov processed this data on August 20, 2015
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Hypertension
Intervention: propofol (Drug); Etomidate (Drug); Propofol and Etomidate (Drug)
Phase: Phase 3
Sponsored by: University of Mississippi Medical Center
Official(s) and/or principal investigator(s):
Cynthia A Vaughn, MD, Study Chair, Affiliation: University of Mississippi Medical Center
This study will attempt to show that a combination of drugs, Etomidate and Propofol, provide
a more stable blood pressure when used to put elderly hypertensive patients to sleep than
either drug used alone.
Official title: Does Administration of Etomidate and Propofol if the Anesthetic Induction of the Elderly Hypertensive Patient Provide Superior Blood Pressure Stability in Response to Direct Laryngosacopy, When Compared to Propofol or Etomidate Alone?
Study design: Allocation: Randomized, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Parallel Assignment, Masking: Open Label
Primary outcome: Blood pressure stability during anesthetic induction
Same as above.
Minimum age: 65 Years.
Maximum age: 90 Years.
- Patients at least 65 years old, with a history of hypertension.
- Patients less than 65 years old or without a history of hypertension.
Locations and Contacts
University of Mississippi Medical Center, Jackson, Mississippi 39216, United States
Starting date: July 2012
Last updated: July 12, 2012