The Effect of Intravenous Lidocaine on Allodynia
Information source: University of Alabama at Birmingham
ClinicalTrials.gov processed this data on August 23, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Pain
Intervention: lidocaine (Drug)
Phase: N/A
Status: Active, not recruiting
Sponsored by: University of Alabama at Birmingham Official(s) and/or principal investigator(s): Michael Froelich, MD, MS, Principal Investigator, Affiliation: University of Alabama at Birmingham
Summary
The purpose of this study is to study if lidocaine, given intravenously, reduces pain.
Clinical Details
Official title: The Effect of Intravenous Lidocaine on Allodynia (Carl Koller Grant)
Study design: Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Primary outcome: Pain intensity
Detailed description:
Clinicians use lidocaine intravenously in a fashion that suggests that it might have
analgesic effects. Therefore, we test the hypothesis that lidocaine reduces pain intensity
in response to experimental pain.
Eligibility
Minimum age: 19 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Chronic Regional Pain Syndrome diagnostic criteria by the Work Safe BC. vi
Exclusion Criteria:
- History of Substance abuse
- Other Medications: CRPS patients are expected to be treated for chronic pain, whether
the current treatment regimen interferes with sensory motor testing will be
determined on a case by case basis.
- Coronary Artery Disease (CAD): unstable
- Congestive Heart Failure (CHF): unstable
- Heart Arrhythmia: symptomatic
- Chronic Obstructive Pulmonary Disease (COPD)
- Lidocaine Allergy
- Diagnostic and Statistical Manual of Mental Disorders (Rev IV): Axis I: Common Axis I
disorders include depression, anxiety disorders, bipolar disorder, ADHD, and
schizophrenia. Axis II: borderline personality disorder, schizotypal personality
disorder, antisocial personality disorder, and mild mental retardation.
- Presence of Contraindications for MRI
- Presence of electronically, magnetically, and mechanically activated implants
- Electronically, magnetically, and mechanically activated implants
- Ferromagnetic or electronically operated active devices like automatic cardioverter
defibrillators
- Cardiac pacemakers
- Metallic splinters in the eye
- Ferromagnetic haemostatic clips in the central nervous system (CNS)
- Claustrophobia
- Pregnancy
Locations and Contacts
University of Alabama at Birmingham, Birmingham, Alabama 35249, United States
Additional Information
Starting date: December 2008
Last updated: August 4, 2015
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