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Compare the Efficacy of Acupuncture Therapy and Carbamazepine Oral Dosage in Patients With Carpal Tunnel Syndrome by Multiple Excitability Test

Information source: Taipei Medical University WanFang Hospital
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Carpal Tunnel Syndrome; Multiple Excitability Test

Intervention: Carbamazepine (Drug); Acupuncture (Procedure)

Phase: N/A

Status: Recruiting

Sponsored by: Taipei Medical University WanFang Hospital

Official(s) and/or principal investigator(s):
Jia-Ying Sung, MD, Principal Investigator, Affiliation: Taipei Medical University-Wan Fang Hospital

Overall contact:
Jia-Ying Sung, MD, Phone: +886-2-2930-7930, Ext: 6940, Email: 96317@wanfang.gov.tw

Summary

The goal of the study is to utilize BCTQ(Boston Carpal Tunnel Questionnaire), VAS (Visual Analog Scale), NCS (Nerve Conduction Study), and MET(Multiple Excitability Test) to evaluate and compare the efficacy of Acupuncture Therapy and Carbamazepine in Patients with Carpal Tunnel Syndrome.

Clinical Details

Official title: A Single-center, Prospective, Randomized, Positive Controlled, Parallel Design Trial to Compare the Efficacy of Acupuncture Therapy and Carbamazepine Oral Dosage in Patients With Carpal Tunnel Syndrome by Multiple Excitability Test

Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Primary outcome: Use QtracW and NCS to evaluate the changes between pre-treatment and post-treatment in patients in both arms.

Secondary outcome:

use BCTQ to evaluate the efficacy of 2 arms at week 4 and at week 12.

use VAS to evaluate the efficacy of 2 arms at week 5, 8 and 12.

Use Quality of Life questionnaire to compare the efficacy of 2 arms at week 12.

Evaluate the safety of 2 arms during the study period

Eligibility

Minimum age: 20 Years. Maximum age: N/A. Gender(s): Both.

Criteria:

Inclusion Criteria:

- Age greater than 20 years old

- outpatient or inpatient subject with numbness of arm, clinically met diagnostic

criteria of AAEM(American association of Electrodiagnostic Medicine CTS task force), and proven to have distal motor neurological disorder through nerve Conduction Study (distal motor latency >4. 6 msec, decreased SNAP < 12uV or prolonged median sensory distal latency (palm to wrist) > 2. 5msec)。

- Willing to sign the Informed Consent form

Exclusion Criteria:

- subject with external hand injury or disformation

- subject with Polyneuritis or Cervical nerve root lesions

- Subject with peripheral hypertrophy, hypothyroidism, multiple myeloma, or amyloidosis

- Allergic to Carbamazepine or similar type of medicine

- inability to act independently, or in the opinion of the investigator, not suitable

for the study

- In the opinion of the investigator, the subject requires surgical repair of the

Carpal Tunnel Syndrome, or the symptoms will be worsen result in irreversible damage to the subject if not treated with surgical repair within 3 months.

Locations and Contacts

Jia-Ying Sung, MD, Phone: +886-2-2930-7930, Ext: 6940, Email: 96317@wanfang.gov.tw

Taipei Medical University - Wan Fang Hospital, Taipei 116, Taiwan; Recruiting
Jia-Ying Sung, MD, Phone: +886-2-2930-7930, Ext: 6940, Email: 96317@wanfang.gov.tw
Jia-Ying Sung, MD, Principal Investigator
Additional Information

Starting date: May 2009
Last updated: April 11, 2011

Page last updated: August 23, 2015

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