Comprehensive Strategy to Decolonize Methicillin-resistant Staphylococcus Aureus (MRSA) in the Outpatient Setting
Information source: University of Calgary
Information obtained from ClinicalTrials.gov on February 07, 2013
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Methicillin-resistant Staphylococcus Aureus
Intervention: pharmacological decolonization treatment (Drug); Education (Behavioral)
Phase: N/A
Status: Recruiting
Sponsored by: University of Calgary Official(s) and/or principal investigator(s):
Thomas J Louie, MD, Principal Investigator, Affiliation: University of Calgary
Overall contact:
Joseph Kim, MD, Phone: 403 944 8090, Email: joskim@ucalgary.ca
Summary
The purpose of this study is to determine the effectiveness of topical and oral antibiotics
in eliminating carriage of methicillin-resistant Staphylococcus aureus (MRSA) among those
living in the community. We hypothesize that a greater proportion of those who receive
intervention will eliminate MRSA carriage compared to those who do not receive any
intervention.
Clinical Details
Official title: Comprehensive Strategy to Decolonize Methicillin-resistant Staphylococcus Aureus in the Outpatient Setting: a Randomized Controlled Study
Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Primary outcome: Eradication of MRSA carriage
Secondary outcome: Occurrence of MRSA infection
Eligibility
Minimum age: 18 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Prior MRSA infection (i. e index case)
- Identified as being colonized with MRSA on initial screen
Exclusion Criteria:
- Are pregnant or breastfeeding.
- Have indwelling catheters.
- Received prior decolonization treatment within last 6 months of enrollment.
- Have allergy to study medication.
- Are colonized with MRSA strain resistant to study medication.
- Have active infection requiring systemic antimicrobials.
- Are household contacts to index case.
Locations and Contacts
Joseph Kim, MD, Phone: 403 944 8090, Email: joskim@ucalgary.ca
Foothills Medical Center, Calgary, Alberta T2N 2T9, Canada; Recruiting
Joseph Kim, MD, Phone: 403 944 8090, Email: joskim@ucalgary.ca
Brendan Byrne, RN, Phone: 403 944 2038
Thomas J Louie, MD, Principal Investigator
Joseph Kim, MD, Sub-Investigator
John M Conly, MD, Sub-Investigator
Elizabeth A Henderson, PhD, Sub-Investigator
Reg Sauve, MD, Sub-Investigator
Kunyan Zhang, MD, Sub-Investigator
Additional Information
Starting date: July 2010
Last updated: November 1, 2010
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