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Low Dose of Midazolam is Superior to Conventional Dose for Rapid Sequence Intubation in Emergency Department (ED)

Information source: Seoul National University Hospital
ClinicalTrials.gov processed this data on August 20, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Intubation

Intervention: Low dose midazolam (Drug)

Phase: N/A

Status: Completed

Sponsored by: Seoul National University Hospital

Summary

Midazolam has been used in rapid sequence intubation for a long time, and the recommended dose is 0. 1mg/kg. In some studies, however, the reduced dose has been used with the concern of hemodynamic instability. We would like to investigate that the low dose midazolam could be used rather than the standard recommended dose, and also compare it to the etomidate, recently used sedatives, with respect to the side effects and the easy performance of intubation.

Clinical Details

Study design: Primary Purpose: Treatment

Eligibility

Minimum age: 18 Years. Maximum age: 90 Years. Gender(s): Both.

Criteria:

Inclusion Criteria:

- patients who need rapid sequence intubation in emergency room

Exclusion Criteria:

- in hypotension(systolic blood pressure less than 90 mmHg

- severe trauma patients

- pregnant

- allergic to midazolam, etomidate

Locations and Contacts

Boramae Medical Center, Seoul 156-707, Korea, Republic of

Seoul National University Bundang Hospital, Emergency room, Seongnam-si, Gyeonggi-do 463-707, Korea, Republic of

Additional Information

Starting date: October 2008
Last updated: July 25, 2011

Page last updated: August 20, 2015

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