Low Dose of Midazolam is Superior to Conventional Dose for Rapid Sequence Intubation in Emergency Department (ED)
Information source: Seoul National University Hospital
ClinicalTrials.gov processed this data on August 20, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Intubation
Intervention: Low dose midazolam (Drug)
Phase: N/A
Status: Completed
Sponsored by: Seoul National University Hospital
Summary
Midazolam has been used in rapid sequence intubation for a long time, and the recommended
dose is 0. 1mg/kg. In some studies, however, the reduced dose has been used with the concern
of hemodynamic instability. We would like to investigate that the low dose midazolam could
be used rather than the standard recommended dose, and also compare it to the etomidate,
recently used sedatives, with respect to the side effects and the easy performance of
intubation.
Clinical Details
Study design: Primary Purpose: Treatment
Eligibility
Minimum age: 18 Years.
Maximum age: 90 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- patients who need rapid sequence intubation in emergency room
Exclusion Criteria:
- in hypotension(systolic blood pressure less than 90 mmHg
- severe trauma patients
- pregnant
- allergic to midazolam, etomidate
Locations and Contacts
Boramae Medical Center, Seoul 156-707, Korea, Republic of
Seoul National University Bundang Hospital, Emergency room, Seongnam-si, Gyeonggi-do 463-707, Korea, Republic of
Additional Information
Starting date: October 2008
Last updated: July 25, 2011
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