Low Dose of Midazolam is Superior to Conventional Dose for Rapid Sequence Intubation in Emergency Department (ED)
Information source: Seoul National University Hospital
Information obtained from ClinicalTrials.gov on October 19, 2009
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Intubation
Intervention: Low dose midazolam (Drug)
Phase: N/A
Status: Recruiting
Sponsored by: Seoul National University Hospital Overall contact:
Kyuseok Kim, MD, PhD, Phone: +82-31-787-3049, Email: dremkks@snubh.org
Summary
Midazolam has been used in rapid sequence intubation for a long time, and the recommended
dose is 0. 1mg/kg. In some studies, however, the reduced dose has been used with the concern
of hemodynamic instability. We would like to investigate that the low dose midazolam could
be used rather than the standard recommended dose, and also compare it to the etomidate,
recently used sedatives, with respect to the side effects and the easy performance of
intubation.
Clinical Details
Study design: Treatment
Eligibility
Minimum age: 18 Years.
Maximum age: 90 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- patients who need rapid sequence intubation in emergency room
Exclusion Criteria:
- in hypotension(systolic blood pressure less than 90 mmHg
- severe trauma patients
- pregnant
- allergic to midazolam, etomidate
Locations and Contacts
Kyuseok Kim, MD, PhD, Phone: +82-31-787-3049, Email: dremkks@snubh.org
Boramae Medical Center, Seoul 156-707, Korea, Republic of; Recruiting
Joong Sik Jeong, MD, Phone: +-82-870-1119, Email: drlunch@medimail.co.kr
Seoul National University Bundang Hospital, Emergency room, Seongnam-si, Gyeonggi-do 463-707, Korea, Republic of; Recruiting
Tae Youn Kim, MD, Phone: +82-31-787-7573, Email: emkity@snubh.org
Additional Information
Starting date: October 2008
Last updated: October 31, 2008
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