A Comparison of Etomidate and Ketamine for Anesthesia Induction in Coronary Artery Bypass Graft Surgery
Information source: Baskent University
ClinicalTrials.gov processed this data on August 20, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Coronary Artery Bypass Surgery
Intervention: Ketamine (Drug); Etomidate (Drug)
Phase: Phase 4
Status: Recruiting
Sponsored by: Baskent University Official(s) and/or principal investigator(s): Özgür Kömürcü, Principal Investigator, Affiliation: Baskent University, Faculty of Medicine
Overall contact: Özgür Kömürcü, Phone: +90 312 215 99 41, Email: zgrkom@gmail.com
Summary
The aim of this study is to determine whether ketamine is an acceptable alternative to
etomidate for anesthesia induction in coronary artery bypass graft surgery in terms of
hemodynamic stability and also to compare these agents regarding their effect on adrenal
gland steroid synthesis in these patients.
Clinical Details
Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Primary outcome: A more than 15% change in mean arterial pressure and heart rate after anesthesia induction
Secondary outcome: Adrenal gland steroid synthesis suppression
Eligibility
Minimum age: 30 Years.
Maximum age: 80 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Patients scheduled for elective coronary artery bypass graft surgery with
cardiopulmonary bypass
- Patient's written informed consent for study participation
- Ejection fraction ≥ 35%
Exclusion Criteria:
- Allergy to study drugs
- Redo surgery
Locations and Contacts
Özgür Kömürcü, Phone: +90 312 215 99 41, Email: zgrkom@gmail.com
Baskent University, Faculty of Medicine, Ankara, Çankaya 06490, Turkey; Recruiting
Additional Information
Starting date: March 2011
Last updated: June 30, 2011
|