Antiemetic Effect of the Addition of Ondansetron to the Morphine Solution in Patient-Controlled Analgesia (PCA)
Information source: Khon Kaen University
Information obtained from ClinicalTrials.gov on June 20, 2008
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Postoperative Nausea and Vomiting
Intervention: ondansetron adding in PCA (Drug)
Sponsored by: Khon Kaen University
Official(s) and/or principal investigator(s):
Polpun Boonmak, MD, Study Director, Affiliation: lecturer in Khon Kaen University
PCA morphine always introduces nausea and vomiting during the postoperative period.
Ondansetron can reduce PONV (postoperative nausea vomiting). We, the researchers at Khon
Kaen University, are trying to add ondansetron in PCA morphine. Patients receive a small dose
of ondansetron when they request morphine.
Study design: Treatment, Randomized, Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Placebo Control, Parallel Assignment, Efficacy Study
Primary outcome: PONV
Minimum age: 15 Years.
Maximum age: 60 Years.
- Age between 15-60 years old
- History of motion sickness, smoking
Locations and Contacts
Khon Kaen university, Srinagarind Hospital, Muang, Khon Kaen 40002, Thailand
Starting date: January 2005
Last updated: October 31, 2007