Intravenous Ketorolac for Postoperative Pain in Percutaneous Nephrolithotomy
Information source: Mayo Clinic
Information obtained from ClinicalTrials.gov on October 04, 2010
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Percutaneous Nephrolithotomy; Kidney Stones
Intervention: Ketorolac (Drug); Placebo (Drug)
Phase: Phase 4
Status: Recruiting
Sponsored by: Mayo Clinic Official(s) and/or principal investigator(s):
Mitchell R. Humphreys, M.D., Principal Investigator, Affiliation: Mayo Clinic
Overall contact:
Laurie Mihalik, Phone: 480-301-8000, Email: mihalik.laurie@mayo.edu
Summary
The purpose of this study is to determine whether continuous intravenous ketorolac infusion
reduces pain in patients who are having percutaneous nephrolithotomy for kidney stone
disease.
Clinical Details
Official title: The Efficacy of Continuous Intravenous Ketorolac for Postoperative Pain in Percutaneous Nephrolithotomy: a Double Blinded Randomized Placebo Controlled Trial
Study design: Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Primary outcome: Pain 'right now'Morphine equivalents of concomitant pain medication
Eligibility
Minimum age: 18 Years.
Maximum age: 65 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Patients undergoing percutaneous nephrolithotomy for kidney stone disease
Exclusion Criteria:
- History of NSAID allergy
- Asthma
- History of long-term opioid use
- Intraoperative blood loss greater than 300 mL
- Postoperative hemodynamic instability
- Active peptic ulcer disease
- Advanced renal impairment (Cr > 2. 0 mg/dL)
- Bleeding diathesis
- Current use of probenecid
- Pregnancy
Locations and Contacts
Laurie Mihalik, Phone: 480-301-8000, Email: mihalik.laurie@mayo.edu
Mayo Clinic, Phoenix, Arizona 85054, United States; Recruiting
Additional Information
Mayo Clinic Clinical Trials
Starting date: October 2008
Last updated: May 4, 2010
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