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Effect of Methyldopa on Uterine Artery Diameter in Pregnant Women With Mild Preeclampsia

Information source: Isfahan University of Medical Sciences
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Pregnant Women With Mild Preeclampsia

Intervention: Methyldopa (Drug); Placebo (Drug)

Phase: Phase 2

Status: Completed

Sponsored by: Isfahan University of Medical Sciences


The present study examined the effects of Methyldopa on uterine artery diameter, uterine artery blood flow, umbilical artery and fetal middle-cerebral artery in patients with Preeclampsia, using Doppler ultrasound.

Clinical Details

Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Primary outcome: Doppler indices


Minimum age: N/A. Maximum age: N/A. Gender(s): Female.


They met the inclusion criteria, If they had over 25 weeks of gestational age, no history of chronic hypertension, no diabetes mellitus, no chronic systemic diseases, no collagen vascular diseases and antiphospholipid syndromes, no use of antihypertensive drugs and BMI higher than 19 and lower than 30 (kg/m2).

Locations and Contacts

Additional Information

Starting date: August 2011
Last updated: August 27, 2012

Page last updated: August 23, 2015

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