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The Effects of Escitalopram on Cytokines

Information source: Beitou Armed Forces Hospital, Taipei, Taiwan
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Depression

Intervention: Escitalopram (Drug)

Phase: N/A

Status: Recruiting

Sponsored by: Beitou Armed Forces Hospital, Taipei, Taiwan

Official(s) and/or principal investigator(s):
Peishen Ho, M.D., Study Chair, Affiliation: Beitou Armed Forces Hospital

Overall contact:
Pei-Shen Ho, M.D., Phone: +886-2-28959808, Email: luke_and_tina@yahoo.com.tw

Summary

The association of cytokines with escitalopram has not been investigated in patients with major depressive disorder (MDD). Hence, the investigators will examine this association.

Clinical Details

Official title: The Effects of Escitalopram on Cytokines in Depressive Patients

Study design: Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Primary outcome: The changes in cytokines

Secondary outcome: The changes in Hamilton Depression Rating Scale

Detailed description: In addition to serotonin, inflammatory process has been suggested in the development of major depressive disorder (MDD) and in its associated treatment. Escitalopram is an antidepressant that has been widely used in patients with MDD because of the promising results. The association of cytokines with escitalopram has not been investigated in patients with MDD. Hence, the investigators will examine this association.

Eligibility

Minimum age: 20 Years. Maximum age: 65 Years. Gender(s): Both.

Criteria:

Inclusion Criteria: 1. DSM-IV-defined Major depressive disorder, single episode 2. Age 20-65 3. Drug-naive 4. Hamilton Depression Rating Scale exceeding 14 scores Exclusion Criteria: 1. Major medical disorders 2. Substance use 3. Pregnant 4. Allergy to escitalopram

Locations and Contacts

Pei-Shen Ho, M.D., Phone: +886-2-28959808, Email: luke_and_tina@yahoo.com.tw

Beitou Armed Forces Hospital, Taipei, Taiwan; Recruiting
Chih-Sung Liang, M.D., Phone: +886-2-8959808, Email: lcsyfw@gmail.com
Additional Information

Starting date: April 2012
Last updated: May 13, 2012

Page last updated: August 23, 2015

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