Effects of Oxybutynin Topical Gel on Gastric Emptying
Information source: Watson Pharmaceuticals
ClinicalTrials.gov processed this data on August 23, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Healthy
Intervention: Oxybutynin Chloride Gel (Drug); Placebo Gel (Drug)
Phase: Phase 1
Status: Completed
Sponsored by: Watson Pharmaceuticals Official(s) and/or principal investigator(s): Scott Olsen, MPH, Study Director, Affiliation: Watson Laboratories
Summary
This study explores the effect of oxybutynin topical gel on gastric emptying
Clinical Details
Official title: Effect of Oxybutynin Chloride Topical Gel on Gastric Emptying, Using the Acetaminophen Absorption Test
Study design: Allocation: Randomized, Endpoint Classification: Pharmacokinetics Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Basic Science
Primary outcome: The effect of oxybutynin chloride topical gel administration on gastric emptying will be assessed by comparing the single dose relative bioavailability of acetaminophen
Eligibility
Minimum age: 18 Years.
Maximum age: N/A.
Gender(s): Female.
Criteria:
Inclusion Criteria:
- Adult, healthy, post-menopausal females
Exclusion Criteria:
- Patients for whom OTG or acetaminophen is contraindicated.
- Abnormality of the GI tract.
- Taking drugs that affect gastric motility.
Locations and Contacts
St. Charles, Missouri, United States
Additional Information
Starting date: June 2009
Last updated: October 5, 2012
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