Efficacy of Cantharidin in Molluscum Contagiosum
Information source: The University of North Carolina, Chapel Hill
Information obtained from ClinicalTrials.gov on October 19, 2009
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Molluscum Contagiosum, Skin Disease
Intervention: cantharidin's vehicle (Drug); Cantharidin 0.7% (Drug)
Phase: N/A
Status: Recruiting
Sponsored by: The University of North Carolina, Chapel Hill Official(s) and/or principal investigator(s):
Jacquelyn R Coloe, BS, Principal Investigator, Affiliation: UNC
Overall contact:
Jacquelyn R Coloe, BS, Phone: 631-678-8537, Email: jcoloe@med.unc.edu
Summary
The University of North Carolina Department of Dermatology is conducting a clinical trial to
evaluate a drug called cantharidin in the treatment of molluscum contagiosum. Molluscum is
a common dermatologic disorder caused by a poxvirus. Molluscum typically presents with many
flesh-colored bumps on the skin. It goes away on its own, though can last several months to
several years. Cantharidin is a topical medicine which is applied at the clinic visit. It
is well tolerated by the majority of children.
Clinical Details
Official title: Efficacy of Cantharidin in Molluscum Contagiosum: A Randomized, Blinded, Placebo-Controlled Prospective Study
Study design: Treatment, Randomized, Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Active Control, Parallel Assignment, Safety/Efficacy Study
Primary outcome: Complete clearance of all molluscum lesions.
Secondary outcome: Partial clearance of molluscum lesions.Association of clinical course with presence of atopic dermatitis.
Eligibility
Minimum age: 5 Years.
Maximum age: 10 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Anyone aged 5-10 years with the clinical diagnosis of molluscum contagiosum.
Exclusion Criteria:
- Anyone with immunosuppression including HIV or previous organ transplantation.
- Anyone taking immunosuppressive medications.
- Anyone who has previously received treatment with cantharidin.
- Any female who has had her first menstrual period.
Locations and Contacts
Jacquelyn R Coloe, BS, Phone: 631-678-8537, Email: jcoloe@med.unc.edu
University of North Carolina, Chapel Hill, North Carolina 27514, United States; Recruiting
Jacquelyn R Coloe, Phone: 919-966-1647, Email: jcoloe@med.unc.edu
Jacquelyn R Coloe, Principal Investigator
Additional Information
Starting date: January 2008
Last updated: March 2, 2009
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