Risk Factors for Linezolid Resistance in Staphylococcus Aureus
Information source: University of Pittsburgh
Information obtained from ClinicalTrials.gov on October 19, 2009
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Linezolid Resistance; Staphylococcus Aureus
Phase: N/A
Status: Recruiting
Sponsored by: University of Pittsburgh Official(s) and/or principal investigator(s):
Brian Potoski, PharmD, Principal Investigator, Affiliation: University of Pittsburgh
Overall contact:
Brian Potoski, PharmD, Phone: 412-648-6487, Email: potoskiba@upmc.edu
Summary
This is a retrospective chart review study. The proposed study aims to document the risk
factors for quinolone resistance in bloodstream isolates of Klebsiella species.
Additionally, the adequacy of empiric antibiotic therapy for Klebsiella bloodstream
infections will be assessed.
Clinical Details
Official title: Risk Factors for Linezolid Resistance in Staphylococcus Aureus
Study design: Cohort, Retrospective
Detailed description:
This is a retrospective chart review study. The proposed study aims to document the risk
factors for quinolone resistance in bloodstream isolates of Klebsiella species.
Additionally, the adequacy of empiric antibiotic therapy for Klebsiella bloodstream
infections will be assessed. This research is important because identification of risk
factors may allow earlier initiation of appropriate therapy in patients infected with these
bacteria. Additionally, we will identify whether horizontal spread is responsible for this
increasing trend.
Eligibility
Minimum age: 18 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- patients with linezolid resistance to staphylococcus aureus
Exclusion Criteria:
- those that don't meet entry criteria
Locations and Contacts
Brian Potoski, PharmD, Phone: 412-648-6487, Email: potoskiba@upmc.edu
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, United States; Recruiting
Brian Potoski, PharmD, Phone: 412-648-6487, Email: potoskiba@upmc.edu
Diana Lynn Pakstis, RN, BSN, Phone: 412-648-6553, Email: pakstisdl@dom.pitt.edu
Brian Potoski, PharmD, Principal Investigator
Additional Information
Starting date: August 2007
Ending date: July 2010
Last updated: April 7, 2009
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