Comparative Pain Control Between 0.2 or 0.3 Spinal Morphine and 0.25 or 0.5 % Bupivacaine for FNB After TKA
Information source: Mahidol University
Information obtained from ClinicalTrials.gov on February 12, 2009
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Post Operative Pain; Total Knee Replacement
Intervention: morphine and bupivacaine (Drug); spinal morphine and marcaine (Drug); morphine and bupivacaine (Drug); morphine and bupivacaine (Drug)
Phase: Phase 4
Status: Not yet recruiting
Sponsored by: Mahidol University Official(s) and/or principal investigator(s):
Thitima Chinachoti, MD, Principal Investigator, Affiliation: Siriraj Hospital
Overall contact:
Thitima Chinachoti, MD, Email: sitci@mahidol.ac.th
Summary
Comparative efficacy of 24 and 48 hours post operative pain control in single total knee
replacement between intrathecal bupivacaine with 0. 2 or 0. 3 mg morphine together with 0. 25 or
0. 5 % bupivacaine for single femoral nerve block
Clinical Details
Official title: Comparative Effect of 0.2 or 0.3 Spinal Morphine and 0.25 or 0.5 % Bupivacaine for Femoral Nerve Block After Total Knee Replacement
Study design: Treatment, Randomized, Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Active Control, Parallel Assignment, Efficacy Study
Primary outcome: Global assessment in post operative pain control
Secondary outcome: Global assessment of post operative pain in 48 HOURS AND SIDE EFFECTS
Eligibility
Minimum age: 45 Years.
Maximum age: 75 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Single elective total knee replacement in ASA 1-3 without significant cardiovascular
limitation
Exclusion Criteria:
- patient at risk in usage COX-2 for post operative pain control
Locations and Contacts
Thitima Chinachoti, MD, Email: sitci@mahidol.ac.th
Siriraj Hospital, Bangkok, Bangkoknoi 10700, Thailand
Additional Information
Starting date: December 2008
Ending date: May 2009
Last updated: November 20, 2008
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