DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Brain Mechanisms Underlying the Effect of the Motilin Receptor Agonist Erythromycin on Hunger in Normal Weight Subjects

Information source: Universitaire Ziekenhuizen Leuven
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Healthy Volunteers

Intervention: Erythromycin (Drug); Placebo (Drug)

Phase: Phase 4

Status: Not yet recruiting

Sponsored by: Universitaire Ziekenhuizen Leuven

Official(s) and/or principal investigator(s):
Jan Tack, Principal Investigator, Affiliation: University of Leuven


The purpose of this study is to investigate the role of erythromycin, a prokinetic agent, on hunger, and the brain mechanism lying behind it.

Clinical Details

Study design: Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Single Blind (Subject), Primary Purpose: Basic Science

Primary outcome: Functional brain images

Secondary outcome:

hunger scores

gut hormones


Minimum age: 18 Years. Maximum age: 60 Years. Gender(s): Female.


Inclusion Criteria:

- Female only.

- Age > 18 and < 60.

- Body Mass Index (BMI) of 19-25 kg/m2 (no weight change of more than 5 kg in the past

three months).

- Not known to have any chronic medical illness or illnesses affecting the

gastrointestinal, cardiovascular, or nervous systems, chronic pain or psychiatric disorder.

- If female not known to be pregnant.

- Not known to have any past upper gastrointestinal surgery.

Exclusion Criteria:

- Alcohol consumption > 7 drinks / week

- Major depression and chronic health conditions except controlled hypertension

Locations and Contacts

Additional Information

Starting date: September 2014
Last updated: August 8, 2014

Page last updated: August 23, 2015

-- advertisement -- The American Red Cross
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017