A Study of Rofecoxib in the Treatment of Post-Operative Pain After Total Knee Joint Replacement.
Information source: Merck
Information obtained from ClinicalTrials.gov on June 20, 2008
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Pain
Intervention: MK0966; rofecoxib (Drug); Comparator: diclofenac 2x 75 mg (Drug)
Phase: Phase 4
Status: Terminated
Sponsored by: Merck Official(s) and/or principal investigator(s):
Medical Monitor, Study Director, Affiliation: Merck
Summary
A study to compare pre-operative administration of rofecoxib versus post-operative
administration of diclofenac or rofecoxib, respectively, in the treatment of post-operative
pain after total knee joint replacement in patients with osteoarthritis of the knee.
Clinical Details
Official title: A Study to Compare Pre-Operative Administration of Rofecoxib Vs Post-Operative Administration of Diclofenac or Rofecoxib in the Treatment of Post-Operative Pain After Total Knee Joint Replacement in Patients With Osteoarthritis of the Knee.
Study design: Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Safety/Efficacy Study
Primary outcome: Quantity of patient controlledPost-operative morphine administration
Eligibility
Minimum age: 18 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Males or females at least 18 years of age who have osteoarthritis of the knee and have
undergone total knee joint replacement.
Locations and Contacts
Msd Sharp & Dohme Gmbh, Haar 85540, Germany
Additional Information
Starting date: January 2004
Last updated: November 30, 2006
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