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Trial Comparing Duration of Analgesia After Popliteal Fossa Sciatiac Nerve Block With Ropivacaine 0.5% When Combined With Placebo, Dexamethasone 4mg or Dexamethasone 8 mg

Information source: Baylor College of Medicine
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Pain, Sciatic Block

Intervention: Placebo (Drug); Dexamethasone 4 mg (Drug); Dexamethasone 8 mg (Drug)

Phase: N/A

Status: Withdrawn

Sponsored by: Baylor College of Medicine

Summary

The purpose is to find out if the addition of dexamethasone to ropivacaine 0. 5% increases the duration of pain relief provided by popliteal sciatic nerve block performed for foot/ankle surgery. The investigators also want to find out if there is a difference between 4 and 8 mg dose of dexamethasone.

Clinical Details

Official title: Randomized, Controlled Trial Comparing Duration of Analgesia After Popliteal Fossa Sciatiac Nerve Block With Ropivacaine 0.5% When Combined With Placebo, Dexamethasone 4mg or Dexamethasone 8 mg

Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Primary outcome: Duration of analgesia

Secondary outcome:

Total pain medication

Pain scores

Eligibility

Minimum age: 18 Years. Maximum age: 64 Years. Gender(s): Both.

Criteria:

Inclusion Criteria:

- Ages 18-64

- ASA Physcial Status classification 1-3

- Foot and ankle surgery at Ben Taub General Hospital

Exclusion Criteria:

- diabetes mellitus

- peripheral neuropathy

- coagulopathy

- allergy to study drugs

- systemic glucocorticoid treatment (for 2 weeks or more) within 6 months of surgery

- chronic opioid use at home

- patient inability to properly describe pain to investigators

- pregancy

- prisoners

- patient or surgeon refusal

Locations and Contacts

Ben Taub General Hospital, Houston, Texas 77030, United States
Additional Information

Starting date: July 2012
Last updated: March 13, 2015

Page last updated: August 23, 2015

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