Evaluation of Negative Symptoms and Cognitive Function After Administration of Antipsychotics in Healthy Volunteer
Information source: Chonbuk National University Hospital
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Normal Volunteers
Intervention: risperidone (Drug); aripiprazole (Drug); haloperidol (Drug); amisulpride (Drug); lactose (Drug)
Phase: N/A
Status: Completed
Sponsored by: Chonbuk National University Hospital
Summary
The aim of the study is to investigate the negative symptoms and cognitive function after
administration of antipsychotics in healthy volunteer.
Clinical Details
Official title: Evaluation of Negative Symptoms and Cognitive Function After Administration of Antipsychotics in Healthy Volunteer: a Double-blind, Randomized Trial of a Single Dose of Placebo, Haloperidol, Amisulpride, Risperidone and Aripiprazole
Study design: Time Perspective: Prospective
Primary outcome: Symptoms assessment by objective and subjective rating scaleSymptoms assessment by objective and subjective rating scales & CNT Symptoms assessment by objective and subjective rating scales
Secondary outcome: Symptoms assessment by objective rating scaleSymptoms assessment by objective rating scale
Eligibility
Minimum age: 18 Years.
Maximum age: 38 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Aged 18-38 years and meet no DSM-IV diagnostic criteria as assessed by using the
Structured Clinical Interview for DSM-IV, research version.
Exclusion Criteria:
- 1) anyone who participated in other clinical trials within 30 days from the start of
this clinical trial or is currently participating in one,
- 2) anyone who has progressive disease or in unstable medical condition unfit for the
trial,
- 3) anyone who has been diagnosed in psychiatric terms in the past, depends on
psychotropic substance, or has overdosed or depended on the substance or alcohol
(except for coffee or tobacco) within 1 month from the trial start,
- 4) anyone who is suicidal or highly probable of suicides, or
- 5) anyone who has test results considered clinically meaningful
Locations and Contacts
Chonbuk national university hospital, Jeonju, Korea, Republic of
Additional Information
Starting date: March 2009
Last updated: August 19, 2010
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