Genetic Epidemiology of Familial Amyotrophic Lateral Sclerosis (ALS)
Information source: Emory University
Information obtained from ClinicalTrials.gov on August 08, 2008
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Amyotrophic Lateral Sclerosis
Phase: N/A
Status: Recruiting
Sponsored by: Emory University Official(s) and/or principal investigator(s):
Michael Benatar, MD, PhD., Principal Investigator, Affiliation: Emory University
Overall contact:
Meraida Polak, RN, Phone: 888-413-9315, Email: fALS@emory.edu
Summary
The investigators' long term goal is to undertake a clinical trial designed to investigate
whether it is possible to delay or prevent the onset of disease amongst people at risk for
developing familial ALS (fALS).
One of the major challenges we, the investigators at Emory University, face, as we consider
the feasibility of a clinical trial, is how to predict who is at greatest risk for developing
ALS within what time frame. In order to try to address this question, we invite all subjects
to undergo genetic testing and to complete a short questionnaire regarding possible
environmental risks (eg. smoking, pesticide exposure, military service and exercise) so that
we can acquire more detailed information about individual and family histories. This
information will then be correlated with the results of the genetic testing in order to
develop statistical models to enable us to predict which subjects are at greatest risk for
developing ALS. This information will help us decide if it is possible to plan a treatment
trial in the future.
Results of genetic testing will not be given to participants.
Clinical Details
Official title: Genetic Epidemiology of Familial Amyotrophic Lateral Sclerosis
Study design: Screening, Cross-Sectional, Defined Population, Retrospective/Prospective Study
Eligibility
Minimum age: 18 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Familial amyotrophic lateral sclerosis
- Related to individuals with familial amyotrophic lateral sclerosis
Exclusion Criteria:
- Under 18 years old
Locations and Contacts
Meraida Polak, RN, Phone: 888-413-9315, Email: fALS@emory.edu
The ALS Center at Emory University, Atlanta, Georgia 30322, United States; Recruiting
Michael Benatar, MD, PhD., Phone: 404-778-3754, Email: mbenata@emory.edu
Jonathan D. Glass, MD, Phone: 404-778-3754, Email: jglas03@emory.edu
Michael Benatar, MD, PhD., Sub-Investigator
Additional Information
Starting date: April 2006
Last updated: April 16, 2007
|
