The Comparison of Supraperiosteal Nerve Block With Opiate Analgesia in Alleviating the Pain of Toothache
Information source: Albany Medical College
Information obtained from ClinicalTrials.gov on November 03, 2008
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Toothache
Intervention: hydrocodone/acetaminophen (Drug); bupivacaine (supraperiosteal nerve block) (Drug)
Phase: Phase 4
Status: Not yet recruiting
Sponsored by: Albany Medical College Official(s) and/or principal investigator(s):
Wayne R Triner, DO, MPH, Principal Investigator, Affiliation: Albany Medical College
Overall contact:
Wayne R Triner, DO, MPH, Phone: 518-262-3773, Email: trinerw@mail.amc.edu
Summary
This study will compare the degree of pain control provided by two techniques for persons
with toothache in an emergency department. The two techniques include;
- standard oral narcotic pain medication
- numbing the tooth with local anesthetic by needle injection
Clinical Details
Official title: The Comparison of Supraperiosteal Nerve Block With Opiate Analgesia in Alleviating the Pain of Toothache
Study design: Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study
Primary outcome: VAS determination of pain at 30 minutes following intervention
Secondary outcome: Numeric scale report or pain
Number of prescribed analgesic pills taken
Detailed description:
Background: Toothache is a common complaint among patients presenting to the emergency
department. There are two commonly employed methods of alleviating this severe form of pain.
Oral opioid analgesia is the most commonly utilized strategy for treating this pain. However,
many emergency physicians and dentists employ a local anesthetic technique known as
supraperiosteal nerve block. This study will compare the relative efficacy of these
techniques.
Patients meeting enrollment criteria will be randomized to either receive a supraperiosteal
nerve block or oral hydrocodone 10 mg/acetaminophen 650 mg. They will otherwise be managed
identically. Reduction of pain scores between entry and 30 minutes post intervention will be
compared as well as numeric pain scores obtained by phone contact 24 hours later. Secondary
outcomes will include the proportion of individuals from each group filling prescriptions for
pain medication and the number of pain pills taken.
Eligibility
Minimum age: 18 Years.
Maximum age: 65 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Involvement of a single tooth
- Percussive tenderness of the crown of the suspect tooth
Exclusion Criteria:
- Age younger than 18 years
- Women who are breast feeding
- Allergy or intolerance to hydrocodone, bupivacaine or acetaminophen
- Pregnancy
- Involvement of multiple teeth
- Pain resulting from pericoronitis.
- Pain resulting from dental trauma occurring less than 90 days prior
- Pain of more than 96 hours duration
- Facial or neck swelling or tenderness
- Alteration in phonation
- Cognitive impairment
- Concurrent use of opiate analgesics
- Impairment of liver function
- Consumption of more than 4 grams of acetaminophen in the past 24 hours.
- Patients who are visually impaired.
Locations and Contacts
Wayne R Triner, DO, MPH, Phone: 518-262-3773, Email: trinerw@mail.amc.edu
Albany Medical Center Hospital, Albany, New York 12208, United States
Additional Information
Starting date: December 2007
Ending date: December 2008
Last updated: December 13, 2007
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