The Counter-irritating Efficacy of Topical Povidone-iodine in Thermal Burns
Information source: Meir Medical Center
Information obtained from ClinicalTrials.gov on February 07, 2013
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Skin Burns
Intervention: povidone iodine (Drug)
Phase: N/A
Status: Not yet recruiting
Sponsored by: Meir Medical Center Official(s) and/or principal investigator(s):
Arieh Bahir, MD, Principal Investigator, Affiliation: Sherute Briut Clalit
Overall contact:
Arieh Bahir, MD, Phone: 0544-522877, Email: abahir@clalit.org.il
Summary
Skin burns are one of the causes of disability, suffering and death in humans. Anecdotal,
uncontrolled studies have shown the efficacy of povidone-iodine ointment in human skin
burns, provided the preparation was applied shortly after the exposure to the heat source.
The proposed study will conduct a controlled study in which the effect of povidone-iodine
ointment will be tested in large group of patients and will be compared with standard cold
water treatment.
Clinical Details
Official title: Testing the Counter-irritating Efficacy of Topical Povidone-iodine in Thermal Burns; Comparison to Conventional Treatments
Study design: Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Primary outcome: prevention of skin lesions caused by exposure to heat source
Secondary outcome: scar prevention
Detailed description:
Skin burns are one of the causes of disability, suffering and death in humans. The current
treatment includes application of cold water or other plant origin preparations. However non
of these treatments was shown to be efficacious.
Animal studies have demonstrated the pronounced protective effect of povidone-iodine
ointment against thermal burns. Moreover, anecdotal, uncontrolled studies in humans have
shown the efficacy of povidone-iodine ointment in human skin burns, provided the preparation
was applied shortly after the exposure to the heat source. The proposed study will conduct a
controlled study in which the effect of povidone-iodine ointment will be tested in large
group of patients and will be compared with standard cold water treatment.
Eligibility
Minimum age: 6 Months.
Maximum age: 18 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- skin burns in children
Exclusion Criteria:
- allergy to iodine
Locations and Contacts
Arieh Bahir, MD, Phone: 0544-522877, Email: abahir@clalit.org.il
Sherute Briut Clalit, Tel Aviv Region, Gush Dan, Heifa, Beer Sheva 59501, Israel; Not yet recruiting
Arieh Bahir, MD, Principal Investigator
Additional Information
Starting date: July 2011
Last updated: May 9, 2011
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